ArticleMateria socio-medica2014
Optic neuritis as first clinical manifestations the multiple sclerosis.
Article in Materia socio-medica, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
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Who cites it
8 citing papers in PubMed.
- Pediatric multiple sclerosis: Improving outcome through high-efficacy therapies.Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics · 2025Review
- A review of multiple sclerosis: From pathophysiology to latest therapeutic advances.AIMS neuroscience · 2025Review
- Incidence of Optic Neuritis among Omani Patients with Multiple Sclerosis at the Sultan Qaboos University Hospital, Muscat, Oman.Sultan Qaboos University medical journal · 2023Article
- Article
- Comparing evolvement of visual field defect in neuromyelitis optica spectrum disorder-optic neuritis and idiopathic optic neuritis: a prospective study.BMC ophthalmology · 2022Article
- Inpatient Ophthalmology Consultations.The Medical clinics of North America · 2021Review
- Analysis of multiple sclerosis patients with electrophysiological and structural tests.International ophthalmology · 2017Article
- Elevated Neutrophil Lymphocyte Ratio in Recurrent Optic Neuritis.Journal of ophthalmology · 2015Article
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Authors and funding
4 authors.
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Abstract
aimTo analyze the clinical signs of multiple sclerosis (MS) and show that optic neuritis is one of the first event, which indicates the development of disease. PATIENTS AND
methodsThe study involved 89 cases in which it confirmed MS at the time of the March 2009-2011. Since ophthalmological parameters were analyzed visual acuity (VA), visual field (VF), and retinal nerve fibre layer (RNFL) thickness of peripapillary rim by optic coherent tomography (OCT).
resultsTen(10) patients had ON as the first clinical manifestation of the disease which was statistically significant (X(2) =9,7 p=0,01) compared to the manifestation of other clinical signs of disease. In VF, centrocecal scotomas were predominant in 50% of the subjects; the RNFL thinning of the neuroretinal rim was verified in all patients, most often in the upper quadrant. A month after pulse corticosteroid therapy, visual acuity in all patients with ON ranged from 0.6 to 1.0.
conclusionON is one of the first MS clinical manifestation. In VF, the most common disturbances are in the centrocecal area. The RNFL thinning was verified in all patients with OCT.
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