Evidence map›Paper›PMID 25395859›Full record

ReviewVascular health and risk management2014

Improving medication adherence in hypercholesterolemia: challenges and solutions.

Justin Gatwood, James E Bailey

Registry-linked trialAbstract readReviewVideo-Audio Media
In one paragraph

Review in Vascular health and risk management, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04458766 (The Use of Mobile Health Technology and Behavioral Economics to Encourage Adherence to Statins in Adolescents With Familial Hypercholesterolemia), which is not on this map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04458766 nacompletednot on this mapstarted 2021, after this paper: background citation

The Use of Mobile Health Technology and Behavioral Economics to Encourage Adherence to Statins in Adolescents With Familial Hypercholesterolemia

TypeinterventionalSponsorBoston Children's HospitalRan2021 to 2024Enrolled11ConditionsFamilial Hypercholesterolemia, Adherence, MedicationArmsMonetary incentives
3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Review
  6. Article
  7. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Justin GatwoodUniversity of Tennessee Health Science Center, College of Pharmacy, Center for Health System Improvement, Memphis, TN, USA.
James E BaileyUniversity of Tennessee Health Science Center, Center for Health System Improvement, Memphis, TN, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Medication nonadherence is a prevalent public health issue that contributes to significant medical costs and detrimental health outcomes. This is especially true in patients with hypercholesterolemia, a condition affecting millions of American adults and one that is associated with increased risk for coronary and cerebrovascular events. Considering the magnitude of outcomes related to this disease, the medical community has placed significant emphasis on addressing the treatment for high cholesterol, and progress has been made in recent years. However, poor adherence to therapy continues to plague health outcomes and more must be understood and done to address suboptimal medication taking. Here we provide an overview of the reasons for poor medication adherence in patients with hypercholesterolemia and describe recent efforts to curb nonadherence. Suggested approaches for improving medication taking in patients with high cholesterol are also provided to guide practitioners, patients, and payers.

Indexed as

Medication AdherenceAnticholesteremic AgentsHealth Knowledge, Attitudes, PracticeHumansHypercholesterolemiaPatient Education as TopicPatientsRisk FactorsTreatment OutcomeAnticholesteremic Agentscardiovascular diseaselipid managementmedication use

Identifiers

PMID25395859
PMCPMC4226449

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.