Evidence map›Paper›PMID 25395659›Full record

ArticleAJNR. American journal of neuroradiology2015

Small pipes: preliminary experience with 3-mm or smaller pipeline flow-diverting stents for aneurysm repair prior to regulatory approval.

A R Martin, J P Cruz, C O'Kelly, M Kelly, J Spears, T R Marotta

Open access · hybridAbstract readMulticenter Study
In one paragraph

Article in AJNR. American journal of neuroradiology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 1 pooled it
1.9field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 1 synthesis or guideline pooled it, 34 citations in OpenAlex.

  1. Safety and efficacy profile of off-label use of the Pipeline Embolization Device: A systematic review and meta-analysis.Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association · 2024
    Pooled it
  2. Outcomes of stent-assisted coil embolization of intracranial aneurysms with a small parental vessel diameter.Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences · 2025
    Article
  3. Article
  4. Article
  5. Article
  6. The Silk Vista Baby - The UK experience.Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences · 2022
    Article
  7. Article
  8. Article
  9. Impact of age on cerebral aneurysm occlusion after flow diversion.Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia · 2019
    Article
  10. Observational
  11. Optimal pediatric dosing of anti-platelet agents for pipeline stent embolization -a case report and review of the literature.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2017
    Review
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

A R MartinFrom the Division of Neurosurgery (A.R.M., J.S.), Department of Surgery allan.martin@utoronto.ca.
J P CruzDepartment of Radiology (J.P.C., T.R.M.), University of Toronto, Toronto, Ontario, Canada.
C O'KellyDivision of Neurosurgery (C.O.), Department of Surgery, University of Alberta, Edmonton, Alberta, Canada.
M KellyDivision of Neurosurgery (M.K.), Department of Surgery, College of Medicine, University of Saskatchewan, Saskatoon, Saskatchewan, Canada.
J SpearsFrom the Division of Neurosurgery (A.R.M., J.S.), Department of Surgery.
T R MarottaDepartment of Radiology (J.P.C., T.R.M.), University of Toronto, Toronto, Ontario, Canada.
University of Toronto · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Flow diversion has become an established treatment option for challenging intracranial aneurysms. The use of small devices of ≤3-mm diameter remains unapproved by major regulatory bodies. A retrospective review of patients treated with Pipeline Embolization Devices of ≤3-mm diameter at 3 Canadian institutions was conducted. Clinical and radiologic follow-up data were collected and reported. Twelve cases were treated with ≥1 Pipeline Embolization Device of ≤3-mm diameter, including 2 with adjunctive coiling, with a median follow-up of 18 months (range, 4-42 months). One patient experienced a posttreatment minor complication (8%) due to an embolic infarct. No posttreatment hemorrhage or delayed complications such as in-stent stenosis/thrombosis were observed. Radiologic occlusion was seen in 9/12 cases (75%) and near-occlusion in 2/12 cases (17%). Intracranial aneurysm treatment with small-diameter flow-diverting stents provided safe and effective aneurysm closure in this small selected sample. These devices should be further studied and considered for regulatory approval.

Indexed as

StentsAdultCanadaDevice ApprovalEmbolization, TherapeuticEndovascular ProceduresEquipment DesignFemaleHumansIntracranial AneurysmMaleMiddle AgedProsthesis DesignRetrospective StudiesTreatment Outcome

Identifiers

PMID25395659
PMCPMC8013041
OpenAlexW1972120380

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.