ArticleDevelopment (Cambridge, England)2014
REVOLUTA and WRKY53 connect early and late leaf development in Arabidopsis.
Article in Development (Cambridge, England), 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 50 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
50 citing papers in PubMed, 1 synthesis or guideline pooled it, 78 citations in OpenAlex.
- Meta-Analysis of Arabidopsis KANADI1 Direct Target Genes Identifies a Basic Growth-Promoting Module Acting Upstream of Hormonal Signaling Pathways.Plant physiology · 2015Pooled it
- Regulatory Network of Leaf Senescence inInternational journal of molecular sciences · 2026Review
- The transcription factor WRKY25 can act as redox switch to drive the expression of WRKY53 during leaf senescence in arabidopsis.Scientific reports · 2025Article
- Comparative Effects of Water Scarcity on the Growth and Development of Two Common Bean (Plants (Basel, Switzerland) · 2024Article
- Mining Heat-Resistant Key Genes of Peony Based on Weighted Gene Co-Expression Network Analysis.Genes · 2024Article
- The Non-JAZ TIFY Protein TIFY8 ofInternational journal of molecular sciences · 2023Article
- Genome-wide identification and characterization of the HD-Zip gene family and expression analysis in response to stress inPlant signaling & behavior · 2022Article
- The CRK5 and WRKY53 Are Conditional Regulators of Senescence and Stomatal Conductance inCells · 2022Article
- The RPN12a proteasome subunit is essential for the multiple hormonal homeostasis controlling the progression of leaf senescence.Communications biology · 2022Article
- Know when and how to die: gaining insights into the molecular regulation of leaf senescence.Physiology and molecular biology of plants : an international journal of functional plant biology · 2022Review
- Mix-and-match: an improved, fast and accessible protocol for hypocotyl micrografting of Arabidopsis seedlings with systemic ACC responses as a case study.Plant methods · 2022Article
- Specificity of HCellular & molecular biology letters · 2022Review
- Article
- The genetic interaction of REVOLUTA and WRKY53 links plant development, senescence, and immune responses.PloS one · 2022Article
- CkREV regulates xylem vessel development inFrontiers in plant science · 2022Article
- Article
- A systems genetics approach to deciphering the effect of dosage variation on leaf morphology in Populus.The Plant cell · 2021Article
- Interaction of gibberellin and other hormones in almond anthers: phenotypic and physiological changes and transcriptomic reprogramming.Horticulture research · 2021Article
- ASCORBATE PEROXIDASE6 delays the onset of age-dependent leaf senescence.Plant physiology · 2021Article
- Multiple Layers of Regulation on Leaf Senescence: New Advances and Perspectives.Frontiers in plant science · 2021Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
As sessile organisms, plants have to continuously adjust growth and development to ever-changing environmental conditions. At the end of the growing season, annual plants induce leaf senescence to reallocate nutrients and energy-rich substances from the leaves to the maturing seeds. Thus, leaf senescence is a means with which to increase reproductive success and is therefore tightly coupled to the developmental age of the plant. However, senescence can also be induced in response to sub-optimal growth conditions as an exit strategy, which is accompanied by severely reduced yield. Here, we show that class III homeodomain leucine zipper (HD-ZIPIII) transcription factors, which are known to be involved in basic pattern formation, have an additional role in controlling the onset of leaf senescence in Arabidopsis. Several potential direct downstream genes of the HD-ZIPIII protein REVOLUTA (REV) have known roles in environment-controlled physiological processes. We report that REV acts as a redox-sensitive transcription factor, and directly and positively regulates the expression of WRKY53, a master regulator of age-induced leaf senescence. HD-ZIPIII proteins are required for the full induction of WRKY53 in response to oxidative stress, and mutations in HD-ZIPIII genes strongly delay the onset of senescence. Thus, a crosstalk between early and late stages of leaf development appears to contribute to reproductive success.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.