Evidence map›Paper›PMID 25394858›Full record

ReviewCurrent neurology and neuroscience reports2015

Nanotheragnostic applications for ischemic and hemorrhagic strokes: improved delivery for a better prognosis.

Tarek H Mouhieddine, Muhieddine M Itani, Amaly Nokkari, Changhong Ren, Georges Daoud, Asad Zeidan, Stefania Mondello, Firas H Kobeissy

Abstract readReview
PubMed Publisher
In one paragraph

Review in Current neurology and neuroscience reports, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
  4. Review
  5. Review
  6. Review
  7. Review
  8. Review
  9. Review
  10. Review
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Tarek H MouhieddineFaculty of Medicine, American University of Beirut Medical Center, Beirut, Lebanon, tarek.mouhieddine@gmail.com.
Muhieddine M Itani
Amaly Nokkari
Changhong Ren
Georges Daoud
Asad Zeidan
Stefania Mondello
Firas H Kobeissy

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Stroke is the second leading cause of death worldwide and a major cause of long-term severe disability representing a global health burden and one of the highly researched medical conditions. Nanostructured material synthesis and engineering have been recently developed and have been largely integrated into many fields including medicine. Recent studies have shown that nanoparticles might be a valuable tool in stroke. Different types, shapes, and sizes of nanoparticles have been used for molecular/biomarker profiling and imaging to help in early diagnosis and prevention of stroke and for drug/RNA delivery for improved treatment and neuroprotection. However, these promising applications have limitations, including cytotoxicity, which hindered their adoption into clinical use. Future research is warranted to fully develop and effectively and safely translate nanoparticles for stroke diagnosis and treatment into the clinic. This work will discuss the emerging role of nanotheragnostics in stroke diagnosis and treatment applications.

Indexed as

AnimalsBrain IschemiaDrug Delivery SystemsHumansIntracranial HemorrhagesNanoparticlesNeuroprotective AgentsPrognosisStrokeNeuroprotective Agents

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.