Evidence map›Paper›PMID 25394191›Full record

ArticleJournal of acquired immune deficiency syndromes (1999)2015

Traumatic stress and the mediating role of alcohol use on HIV-related sexual risk behavior: results from a longitudinal cohort of South African women who attend alcohol-serving venues.

Laurie Abler, Kathleen J Sikkema, Melissa H Watt, Eileen V Pitpitan, Seth C Kalichman, Donald Skinner, Desiree Pieterse

Abstract read
In one paragraph

Article in Journal of acquired immune deficiency syndromes (1999), 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Laurie Abler*Duke Global Health Institute, Duke University, Durham, NC; †Department of Psychology and Neuroscience, Duke University, Durham, NC; ‡Division of Global Public Health, Department of Medicine, University of California San Diego, San Diego, CA; §Department of Psychology, University of Connecticut, Storrs, CT; and ‖Unit for Research on Health and Society, Stellenbosch University, Tygerberg, South Africa.
Kathleen J Sikkema
Melissa H Watt
Eileen V Pitpitan
Seth C Kalichman
Donald Skinner
Desiree Pieterse

Funding

Social and Behavioral Sciences CoreP30AI064518 · NIAID · DUKE UNIVERSITY · PI Nwora Lance Okeke · 2005 to 2026
$50.5M
Alcohol-Related HIV Risks among South African WomenR01AA018074 · NIAAA · UNIVERSITY OF CONNECTICUT STORRS · PI KALICHMAN, SETH C, SIKKEMA, KATHLEEN J · 2008 to 2012
$2.9M
Venue-level Risks for HIV/STI among Male Clients of FSWs in Tijuana, MexicoK01DA036447 · NIDA · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI PITPITAN, EILEEN VIRTUSIO · 2014 to 2018
$938k
NIAAA NIH HHS R01 AA018074NIAAA NIH HHS R01AA018074NIAID NIH HHS P30 AI064518NIDA NIH HHS K01 DA036447
6 · The paper itself

Abstract

backgroundIn South Africa, alcohol contributes to the HIV epidemic, in part, by influencing sexual behaviors. For some, high levels of alcohol consumption may be driven by previous traumatic experiences that result in traumatic stress. The purpose of this study was to quantify the longitudinal association between traumatic stress and unprotected sex among women who attend drinking venues and to assess whether this association was explained by mediation through alcohol use.

methodsData were collected in 4 waves over a year from a prospective cohort of 560 women who regularly attended alcohol-serving venues in a Cape Town township. Longitudinal mixed models examined (1) the relationship between traumatic stress and counts of unprotected sex and (2) whether alcohol use mediated the association between traumatic stress and unprotected sex.

resultsMost women reported elevated traumatic stress (80%) and hazardous alcohol use (88%) at least once during the study period. In models adjusted for covariates, traumatic stress was associated with unprotected sex (b = 0.28, SE = 0.06, t = 4.82, P < 0.001). In addition, traumatic stress was associated with alcohol use (b = 0.27, SE = 0.02, t = 14.25, P < 0.001) and was also associated with unprotected sex (b = 0.20, SE = 0.06, t = 3.27, P < 0.01) while controlling for alcohol use (b = 0.28, SE = 0.07, t = 4.25, P < 0.001). The test for the mediated effect established that alcohol use was a significant mediator, accounting for 27% of the total effect of traumatic stress on unprotected sex.

conclusionsThese results highlight the need to address traumatic stress among female venue patrons as an important precursor of HIV risk due to alcohol use.

Indexed as

Alcohol DrinkingRisk-TakingStress, PsychologicalAdolescentAdultCohort StudiesFemaleHIV InfectionsHumansLongitudinal StudiesMiddle AgedProspective StudiesSouth AfricaUnsafe SexYoung Adult

Identifiers

PMID25394191
PMCPMC4326588

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.