ArticlePLoS pathogens2014
The plasmodesmal protein PDLP1 localises to haustoria-associated membranes during downy mildew infection and regulates callose deposition.
Article in PLoS pathogens, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 75 papers, 2 of them syntheses that pooled it.
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Who cites it
75 citing papers in PubMed, 2 syntheses or guidelines pooled it, 160 citations in OpenAlex.
- A comparative meta-proteomic pipeline for the identification of plasmodesmata proteins and regulatory conditions in diverse plant species.BMC biology · 2022Pooled it
- Primary nitrate responses mediated by calcium signalling and diverse protein phosphorylation.Journal of experimental botany · 2020Pooled it
- Cysteine-rich secreted protein OsCRRSP1 enhances rice defense through dual inhibition of pathogen and host catalases.Plant communications · 2026Article
- Detecting Callose Deposition in Soybean Lateral Roots During Fungal Infections.Current protocols · 2026Article
- Plasmodesmal closure elicits stress responses.EMBO reports · 2026Article
- The study of plasmodesmal biology using proximity labeling technologies.Journal of experimental botany · 2026Review
- Cell-to-cell connectivity: a future target for crop improvement.Journal of experimental botany · 2026Review
- Foliar-applied double-stranded RNA is mobile, transfers to plant pathogens, and triggers RNAi.Nucleic acids research · 2026Article
- Regulation of Plasmodesmata Function Through Lipid-Mediated PDLP7 or PDLP5 Strategies inPlants (Basel, Switzerland) · 2026Article
- Genome-Wide Analysis of Callose Synthase (CALS) Genes in Cabbage (International journal of molecular sciences · 2025Article
- Woody Host-Specific Type III Effector HopBL2 Is Essential for Pseudomonas savastanoi Virulence and Associates With Plasmodesmata.Molecular plant pathology · 2025Article
- Silencing of Putative Plasmodesmata-Associated GenesPlants (Basel, Switzerland) · 2025Article
- Infiltration-RNAseq Reveals Enhanced Defense Responses inPlants (Basel, Switzerland) · 2025Article
- PDLP5, a plasmodesmata permeability regulator, can traffic between plant cells.NPJ science of plants · 2025Article
- Drought-dependent regulation of cell coupling in Arabidopsis leaf epidermis requires plasmodesmal protein NHL12.Journal of experimental botany · 2024Article
- Selective recognition of PTRE1 transcripts mediated by protein-protein interaction between the mPlant communications · 2024Article
- Confocal Microscopy Analysis of Protein Sorting to Plasmodesmata in Nicotiana benthamiana.Journal of visualized experiments : JoVE · 2024Article
- PLASMODESMATA-LOCATED PROTEIN 6 regulates plasmodesmal function in Arabidopsis vasculature.The Plant cell · 2024Article
- Plasmodesmata-associated Flotillin positively regulates broad-spectrum virus cell-to-cell trafficking.Plant biotechnology journal · 2024Article
- Role of PMR4 and PDLP1 in priming of early acting penetration defense by resistance-inducing β-amino acids.iScience · 2024Article
15 more citing papers are in PubMed but not listed here.
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Authors and funding
9 authors at 3 institutions in 1 country.
Funding
Abstract
The downy mildew pathogen Hyaloperonospora arabidopsidis (Hpa) is a filamentous oomycete that invades plant cells via sophisticated but poorly understood structures called haustoria. Haustoria are separated from the host cell cytoplasm and surrounded by an extrahaustorial membrane (EHM) of unknown origin. In some interactions, including Hpa-Arabidopsis, haustoria are progressively encased by host-derived, callose-rich materials but the molecular mechanisms by which callose accumulates around haustoria remain unclear. Here, we report that PLASMODESMATA-LOCATED PROTEIN 1 (PDLP1) is expressed at high levels in Hpa infected cells. Unlike other plasma membrane proteins, which are often excluded from the EHM, PDLP1 is located at the EHM in Hpa-infected cells prior to encasement. The transmembrane domain and cytoplasmic tail of PDLP1 are sufficient to convey this localization. PDLP1 also associates with the developing encasement but this association is lost when encasements are fully mature. We found that the pdlp1,2,3 triple mutant is more susceptible to Hpa while overexpression of PDLP1 enhances plant resistance, suggesting that PDLPs enhance basal immunity against Hpa. Haustorial encasements are depleted in callose in pdlp1,2,3 mutant plants whereas PDLP1 over-expression elevates callose deposition around haustoria and across the cell surface. These data indicate that PDLPs contribute to callose encasement of Hpa haustoria and suggests that the deposition of callose at haustoria may involve similar mechanisms to callose deposition at plasmodesmata.
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