Evidence map›Paper›PMID 25393617›Full record

ArticleStatistics in medicine2015

A Bayesian approach for instrumental variable analysis with censored time-to-event outcome.

Gang Li, Xuyang Lu

Abstract read
In one paragraph

Article in Statistics in medicine, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact, top 86% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 11 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Gang LiDepartment of Biostatistics, UCLA School of Public Health, Los Angeles, CA 90095-1772, U.S.A.
Xuyang Lu
University of California, Los Angeles · US

Funding

Women's CancersP30CA016042 · NCI · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI JOHN A GLASPY · 1985 to 2026
$134.5M
UCLA Clinical and Translational Science InstituteUL1TR000124 · NCATS · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI DUBINETT, STEVEN M. · 2012 to 2015
$57.0M
UCLA Center for Excellence in Pancreatic DiseasesP01AT003960 · NCCIH · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI GO, VAY LIANG W · 2007 to 2011
$5.6M
NCATS NIH HHS UL1 TR000124NCCIH NIH HHS P01 AT003960NCCIH NIH HHS P01AT003960NCI NIH HHS CA016042NCI NIH HHS P30 CA016042NCRR NIH HHS U54 RR031268-01
6 · The paper itself

Abstract

Instrumental variable (IV) analysis has been widely used in economics, epidemiology, and other fields to estimate the causal effects of covariates on outcomes, in the presence of unobserved confounders and/or measurement errors in covariates. However, IV methods for time-to-event outcome with censored data remain underdeveloped. This paper proposes a Bayesian approach for IV analysis with censored time-to-event outcome by using a two-stage linear model. A Markov chain Monte Carlo sampling method is developed for parameter estimation for both normal and non-normal linear models with elliptically contoured error distributions. The performance of our method is examined by simulation studies. Our method largely reduces bias and greatly improves coverage probability of the estimated causal effect, compared with the method that ignores the unobserved confounders and measurement errors. We illustrate our method on the Women's Health Initiative Observational Study and the Atherosclerosis Risk in Communities Study.

Indexed as

Analysis of VarianceBayes TheoremAtherosclerosisBiostatisticsComputer SimulationFemaleHumansLinear ModelsMaleMarkov ChainsMonte Carlo MethodObservational Studies as TopicRisk FactorsWomen's Healthaccelerated failure time modelBayesian methodinstrumental variable analysismeasurement errorMendelian randomizationtime-to-event outcome

Identifiers

PMID25393617
PMCPMC4314427
OpenAlexW2131832031

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.