Evidence map›Paper›PMID 25393277›Full record

ArticlePloS one2014

Application of 3-dimensional printing technology to construct an eye model for fundus viewing study.

Ping Xie, Zizhong Hu, Xiaojun Zhang, Xinhua Li, Zhishan Gao, Dongqing Yuan, Qinghuai Liu

Abstract read
In one paragraph

Article in PloS one, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
  3. Three-dimensional bioprinting in ophthalmic care.International journal of ophthalmology · 2023
    Review
  4. Review
  5. Review
  6. Application of Bioprinting in Ophthalmology.International journal of bioprinting · 2022
    Review
  7. 3D Printing in Eye Care.Ophthalmology and therapy · 2021
    Review
  8. Article
  9. Article
  10. Article
  11. Review
  12. Three-dimensional printing of the retina.Current opinion in ophthalmology · 2016
    Review
  13. Review
  14. Review
  15. Outlooks on Three-Dimensional Printing for Ocular Biomaterials Research.Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Ping XieDepartment of Ophthalmology, the First Affiliated Hospital of Nanjing Medical University, Nanjing 210029, P.R. China.
Zizhong HuDepartment of Ophthalmology, the First Affiliated Hospital of Nanjing Medical University, Nanjing 210029, P.R. China.
Xiaojun ZhangDepartment of Ophthalmology, the Second Affiliated Hospital of Nanjing Medical University, Nanjing 210000, P.R. China.
Xinhua LiSchool of Optical Engineering, Nanjing University of Science and Technology, Nanjing 210094, P.R. China; Ophthalmic Technology of College, Jinling Institute of Technology, Nanjing, 210001, P.R. China.
Zhishan GaoSchool of Optical Engineering, Nanjing University of Science and Technology, Nanjing 210094, P.R. China.
Dongqing YuanDepartment of Ophthalmology, the First Affiliated Hospital of Nanjing Medical University, Nanjing 210029, P.R. China.
Qinghuai LiuDepartment of Ophthalmology, the First Affiliated Hospital of Nanjing Medical University, Nanjing 210029, P.R. China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo construct a life-sized eye model using the three-dimensional (3D) printing technology for fundus viewing study of the viewing system.

methodsWe devised our schematic model eye based on Navarro's eye and redesigned some parameters because of the change of the corneal material and the implantation of intraocular lenses (IOLs). Optical performance of our schematic model eye was compared with Navarro's schematic eye and other two reported physical model eyes using the ZEMAX optical design software. With computer aided design (CAD) software, we designed the 3D digital model of the main structure of the physical model eye, which was used for three-dimensional (3D) printing. Together with the main printed structure, polymethyl methacrylate(PMMA) aspherical cornea, variable iris, and IOLs were assembled to a physical eye model. Angle scale bars were glued from posterior to periphery of the retina. Then we fabricated other three physical models with different states of ammetropia. Optical parameters of these physical eye models were measured to verify the 3D printing accuracy.

resultsIn on-axis calculations, our schematic model eye possessed similar size of spot diagram compared with Navarro's and Bakaraju's model eye, much smaller than Arianpour's model eye. Moreover, the spherical aberration of our schematic eye was much less than other three model eyes. While in off- axis simulation, it possessed a bit higher coma and similar astigmatism, field curvature and distortion. The MTF curves showed that all the model eyes diminished in resolution with increasing field of view, and the diminished tendency of resolution of our physical eye model was similar to the Navarro's eye. The measured parameters of our eye models with different status of ametropia were in line with the theoretical value.

conclusionsThe schematic eye model we designed can well simulate the optical performance of the human eye, and the fabricated physical one can be used as a tool in fundus range viewing research.

Indexed as

Fundus OculiModels, AnatomicPrinting, Three-DimensionalAstigmatismComputer SimulationCorneaCorneal TopographyHumansLenses, IntraocularPolymethyl MethacrylateRefractive ErrorsPolymethyl Methacrylate

Identifiers

PMID25393277
PMCPMC4230932

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.