Evidence map›Paper›PMID 25393026›Full record

ArticlePLoS genetics2014

Regularized machine learning in the genetic prediction of complex traits.

Sebastian Okser, Tapio Pahikkala, Antti Airola, Tapio Salakoski, Samuli Ripatti, Tero Aittokallio

Abstract read
In one paragraph

Article in PLoS genetics, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 85 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
85citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

85 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Systematic Review of Polygenic Risk Scores for Type 1 and Type 2 Diabetes.International journal of molecular sciences · 2020
    Pooled it
  3. Trial
  4. Article
  5. Discriminating models of trait evolution.Evolution; international journal of organic evolution · 2026
    Article
  6. Review
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25 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Sebastian OkserDepartment of Information Technology, University of Turku, Turku, Finland; Turku Centre for Computer Science (TUCS), University of Turku and Åbo Akademi University, Turku, Finland.
Tapio PahikkalaDepartment of Information Technology, University of Turku, Turku, Finland; Turku Centre for Computer Science (TUCS), University of Turku and Åbo Akademi University, Turku, Finland.
Antti AirolaDepartment of Information Technology, University of Turku, Turku, Finland; Turku Centre for Computer Science (TUCS), University of Turku and Åbo Akademi University, Turku, Finland.
Tapio SalakoskiDepartment of Information Technology, University of Turku, Turku, Finland; Turku Centre for Computer Science (TUCS), University of Turku and Åbo Akademi University, Turku, Finland.
Samuli RipattiHjelt Institute, University of Helsinki, Helsinki, Finland; Institute for Molecular Medicine Finland (FIMM), University of Helsinki, Helsinki, Finland; Wellcome Trust Sanger Institute, Hinxton, United Kingdom.
Tero AittokallioTurku Centre for Computer Science (TUCS), University of Turku and Åbo Akademi University, Turku, Finland; Institute for Molecular Medicine Finland (FIMM), University of Helsinki, Helsinki, Finland.

Funding

Wellcome Trust
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Artificial IntelligenceGenetic Association StudiesGenome-Wide Association StudyHumansModels, Statistical

Identifiers

PMID25393026
PMCPMC4230844

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.