Evidence map›Paper›PMID 25392668›Full record

ArticleJSLS : Journal of the Society of Laparoendoscopic Surgeons

Laparoscopic appendectomy is safer than open appendectomy in an elderly population.

Nicholas T Ward, Sonia L Ramamoorthy, David C Chang, J Kellogg Parsons

Registry-linked trialOpen access · hybridAbstract read
In one paragraph

Article in JSLS : Journal of the Society of Laparoendoscopic Surgeons. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02714023 (Water And Saline Head-to-head In The Blinded Evaluation Study Trial), which is not on this map. Cited by 13 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 3 pooled it
4.1field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02714023 nacompletednot on this map

Water And Saline Head-to-head In The Blinded Evaluation Study Trial

TypeinterventionalSponsorUniversity of Missouri-ColumbiaRan2012 to 2017Enrolled241ConditionsAcute Appendicitis, AbscessArmsNormal Saline, Sterile Water
3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 3 syntheses or guidelines pooled it, 31 citations in OpenAlex.

  1. Guideline
  2. Pooled it
  3. Pooled it
  4. Trial
  5. Article
  6. Risk factors for postoperative morbidity, prolonged length of stay and hospital readmission after appendectomy for acute appendicitis.European journal of trauma and emergency surgery : official publication of the European Trauma Society · 2023
    Article
  7. The role of CT in decision for acute appendicitis treatment.Diagnostic and interventional radiology (Ankara, Turkey) · 2022
    Article
  8. Review
  9. Article
  10. Article
  11. Article
  12. Review
  13. Laparoscopic vs mini-incision open appendectomy.World journal of gastrointestinal surgery · 2015
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Nicholas T WardDepartment of Surgery, UC San Diego Health System, San Diego, CA, USA.
Sonia L RamamoorthyDepartment of Surgery, UC San Diego Health System, San Diego, CA, USA.
David C ChangDepartment of Surgery, UC San Diego Health System, San Diego, CA, USA.
J Kellogg ParsonsDepartment of Surgery, UC San Diego Health System, San Diego, CA, USA.
UC San Diego Health System · USVA San Diego Healthcare System · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND AND

objectivesThis study describes perioperative patient safety outcomes comparing laparoscopic appendectomy with open appendectomy in the elderly population (defined as age≥65 years) during the diffusion of laparoscopic appendectomy into widespread clinical practice.

methodsWe performed a cross-sectional analysis of patients undergoing open or laparoscopic appendectomy in the US Nationwide Inpatient Sample, a 20% sample of inpatient discharges from 1056 hospitals, from 1998 to 2009, and used weighted sampling to estimate national trends. Multivariate logistic regression modeling was used to examine the association of laparoscopy with perioperative outcomes.

resultsPatients who met the inclusion criteria totaled 257,484. Of these, 87,209 (34%) underwent laparoscopic appendectomy. These patients were younger (P<.001); had lower Charlson comorbidity scores (P<.001); were more likely to be white (P<.001), to be privately insured (P=.005), and to undergo surgery in urban hospitals (P<.001); and were less likely to have appendiceal rupture (P<.001). Laparoscopic appendectomy was associated with a decreased length of stay (4.44 days vs 7.86 days, P<.001), fewer total patient safety indicator events (1.8% vs 3.5%, P<.001), and a decreased mortality rate (0.9% vs 2.8%, P<.001). On multivariate analyses, we observed a 32% (odds ratio, 0.68) decreased probability of patient safety events occurring in laparoscopic appendectomy cases versus open appendectomy cases as measured by patient safety indicators.

conclusionThe data suggest that laparoscopic appendectomy is associated with improved clinical outcomes in the elderly and that diffusion of laparoscopic appendectomy is not associated with adverse patient safety events in this population.

Indexed as

AgedAppendectomyAppendicitisCross-Sectional StudiesFemaleHumansLaparoscopyLength of StayMalePatient DischargeAppendectomyPatient safety indicatorSurgery in elderly

Identifiers

PMID25392668
PMCPMC4208904
OpenAlexW2330768971

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.