Evidence map›Paper›PMID 25392587›Full record

ReviewAfrican journal of traditional, complementary, and alternative medicines : AJTCAM2014

Remedial applications of silencing ribonucleic acids and modalities for its delivery to the kidneys--a review.

Dongjie Wang, Yanfen Lv, Huifang Zhu, Guifeng Lv, Jiyi Huang

Open access · diamondAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in African journal of traditional, complementary, and alternative medicines : AJTCAM, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.1field-weighted citation impact, top 46% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Dongjie WangMedical Education Center, Langfang Health Vocational College, 065001. Langfang, Heibei Province, China.
Yanfen LvChildren Health Department, Langfang Women and Children's Health Center, 065000, Langfang, Heibei Province, China.
Huifang ZhuObstetrics and Gynecology Education Center, Langfang Health Vocational College, 065001, Langfang, Heibei Province, China.
Guifeng LvTraditional Chinese Medicine Education Center, Langfang Health Vocational College, 065001, Langfang, Heibei Province, China.
Jiyi HuangNephrology Department, The First Affiliated Hospital of Xiamen University, Tongmin Branch Court, 361000, Xiamen, Fujian Province, China.
Langfang Normal University · CNFirst Affiliated Hospital of Xiamen University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe Kidney has been the target organ for the delivery of silencing ribonucleic acids (silencing RNA) administered systemically in comparison to other body tissues. MATERIALS AND

methodIn this review, we discussed different approaches made to delivering proteins to the kidneys in different conditions like normal and pathological defects. Data from clinical experiments have been used to discuss and support the administration of silencing RNA for the treatment of kidney diseases.

resultsResults were achieved using the available genome wide RNA libraries.

conclusionThe research results are helpful in application to 3D and conventional models to find the involvement of signal pathways in kidney diseases.

Indexed as

Genetic TherapyKidney DiseasesRNARNA InterferenceHumansKidneyProteinsProteinsRNAkidney diseasesignal pathwayssilencing RNAtargeting proteins

Identifiers

PMID25392587
PMCPMC4202403
OpenAlexW2049638483

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.