Evidence map›Paper›PMID 25392501›Full record

ReviewThe Journal of neuroscience : the official journal of the Society for Neuroscience2014

Advances in understanding mechanisms of thalamic relays in cognition and behavior.

Anna S Mitchell, S Murray Sherman, Marc A Sommer, Robert G Mair, Robert P Vertes, Yogita Chudasama

Abstract readReview
In one paragraph

Review in The Journal of neuroscience : the official journal of the Society for Neuroscience, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 87 papers.

0numbers the graph read from it
0cells of the map it votes in
87citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

87 citing papers in PubMed.

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27 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Anna S MitchellDepartment of Experimental Psychology, Oxford University, Oxford OX1 3UD, United Kingdom.ORCID http://orcid.org/0000-0001-8996-1067
S Murray ShermanDepartment of Neurobiology, University of Chicago, Chicago, Illinois 60637.ORCID http://orcid.org/0000-0002-1520-2778
Marc A SommerDepartment of Biomedical Engineering, Duke University, Durham, North Carolina 27708.
Robert G MairDepartment of Psychology, University of New Hampshire, Durham, New Hampshire 03824.ORCID http://orcid.org/0000-0002-5943-2276
Robert P VertesCenter for Complex Systems and Brain Sciences, Florida Atlantic University, Boca Raton, Florida 33431, and.
Yogita ChudasamaDepartment of Psychology, McGill University, Montreal, Quebec H3A 1B1, Canada yogita.chudasama@mcgill.ca.

Funding

Functional relationships between visual cortex and thalamusR01EY022338 · NEI · UNIVERSITY OF CHICAGO · PI SHERMAN, S. MURRAY · 2012 to 2020
$3.6M
Information processing in sensory systemsR01DC008794 · NIDCD · UNIVERSITY OF CHICAGO · PI SHERMAN, S. MURRAY · 2007 to 2016
$3.3M
Visuomotor functions of ascending pathways to frontal cortexR01EY017592 · NEI · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI SOMMER, MARC A · 2006 to 2010
$1.7M
Role of the midline thalamus in arousal, attention and cognitionR15MH099590 · NIMH · FLORIDA ATLANTIC UNIVERSITY · PI VERTES, ROBERT PAUL · 2013 to 2013
$423k
Functions of Saccadic Circuits in Lateral Cerebellar CortexR21EY022788 · NEI · DUKE UNIVERSITY · PI SOMMER, MARC A · 2012 to 2013
$393k
Canadian Institutes of Health Research 102507Medical Research Council G0800329NEI NIH HHS EY-022338NEI NIH HHS R01 EY017592NEI NIH HHS R01EY017592NEI NIH HHS R01 EY022338NEI NIH HHS R21 EY022788NEI NIH HHS R21EY022788NIDCD NIH HHS DC-008794NIDCD NIH HHS R01 DC008794NIMH NIH HHS MH099590NIMH NIH HHS R15 MH099590
6 · The paper itself

Abstract

The main impetus for a mini-symposium on corticothalamic interrelationships was the recent number of studies highlighting the role of the thalamus in aspects of cognition beyond sensory processing. The thalamus contributes to a range of basic cognitive behaviors that include learning and memory, inhibitory control, decision-making, and the control of visual orienting responses. Its functions are deeply intertwined with those of the better studied cortex, although the principles governing its coordination with the cortex remain opaque, particularly in higher-level aspects of cognition. How should the thalamus be viewed in the context of the rest of the brain? Although its role extends well beyond relaying of sensory information from the periphery, the main function of many of its subdivisions does appear to be that of a relay station, transmitting neural signals primarily to the cerebral cortex from a number of brain areas. In cognition, its main contribution may thus be to coordinate signals between diverse regions of the telencephalon, including the neocortex, hippocampus, amygdala, and striatum. This central coordination is further subject to considerable extrinsic control, for example, inhibition from the basal ganglia, zona incerta, and pretectal regions, and chemical modulation from ascending neurotransmitter systems. What follows is a brief review on the role of the thalamus in aspects of cognition and behavior, focusing on a summary of the topics covered in a mini-symposium held at the Society for Neuroscience meeting, 2014.

Indexed as

AnimalsBehaviorCerebral CortexCognitionHumansLearningNeural PathwaysThalamus

Identifiers

PMID25392501
PMCPMC4228136

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.