Evidence map›Paper›PMID 25392485›Full record

ReviewThe Journal of neuroscience : the official journal of the Society for Neuroscience2014

Novel RNA modifications in the nervous system: form and function.

John S Satterlee, Maria Basanta-Sanchez, Sandra Blanco, Jin Billy Li, Kate Meyer, Jonathan Pollock, Ghazaleh Sadri-Vakili, Agnieszka Rybak-Wolf

Open access · bronzeAbstract readReview
In one paragraph

Review in The Journal of neuroscience : the official journal of the Society for Neuroscience, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
34citing papers in PubMed, 1 pooled it
2.4field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

34 citing papers in PubMed, 1 synthesis or guideline pooled it, 67 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Review
  4. Article
  5. Review
  6. mEMBO reports · 2024
    Article
  7. Article
  8. Article
  9. Divergent landscapes of A-to-I editing in postmortem and living human brain.medRxiv : the preprint server for health sciences · 2024
    Article
  10. Article
  11. Review
  12. Article
  13. Article
  14. Epigenetic modification in Parkinson's disease.Frontiers in cell and developmental biology · 2023
    Review
  15. Article
  16. Review
  17. RNA Modifications and RNA Metabolism in Neurological Disease Pathogenesis.International journal of molecular sciences · 2021
    Review
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 7 institutions in 3 countries.

John S SatterleeNational Institute on Drug Abuse, Bethesda, Maryland 20892, satterleej@nida.nih.gov.
Maria Basanta-SanchezRNA Institute, State University at Albany, Albany, New York 12222.ORCID http://orcid.org/0000-0002-1452-8493
Sandra BlancoWellcome Trust, Medical Research Council Stem Cell Institute, University of Cambridge, Tennis Court Road, Cambridge CB2 1QR, United Kingdom.ORCID http://orcid.org/0000-0001-7352-9392
Jin Billy LiStanford University, Department of Genetics, Stanford, California 94305.
Kate MeyerDepartment of Pharmacology, Weill Medical College, Cornell University, New York, New York 10065.
Jonathan PollockNational Institute on Drug Abuse, Bethesda, Maryland 20892.
Ghazaleh Sadri-VakiliMassGeneral Institute for Neurodegenerative Disease, Massachusetts General Hospital, Boston, Massachusetts 02129-4404, and.
Agnieszka Rybak-WolfMax-Delbrück-Centrum für Molekulare Medizin, 13092 Berlin, Germany.
National Institute on Drug Abuse · USAlbany State University · USCornell University · USMassachusetts General Hospital · USMax Delbrück Center · DEStanford University · USWellcome/MRC Cambridge Stem Cell Institute · GB

Funding

Profiling and Dissecting the Dynamic Regulation of RNA EditingR01GM102484 · NIGMS · STANFORD UNIVERSITY · PI LI, JIN BILLY · 2013 to 2021
$3.1M
mRNA Methylation: a Novel Regulatory Mechanism in the Neuronal TranscriptomeK99MH104712 · NIMH · WEILL MEDICAL COLL OF CORNELL UNIV · PI MEYER, KATHRYN D · 2014 to 2015
$180k
NIGMS NIH HHS R01 GM102484NIMH NIH HHS K99 MH104712
6 · The paper itself

Abstract

Modified RNA molecules have recently been shown to regulate nervous system functions. This mini-review and associated mini-symposium provide an overview of the types and known functions of novel modified RNAs in the nervous system, including covalently modified RNAs, edited RNAs, and circular RNAs. We discuss basic molecular mechanisms involving RNA modifications as well as the impact of modified RNAs and their regulation on neuronal processes and disorders, including neural fate specification, intellectual disability, neurodegeneration, dopamine neuron function, and substance use disorders.

Indexed as

AnimalsBrainHumansMethylationReceptors, GlutamateRNARNA, CircularRNA EditingRNA, UntranslatedSubstance-Related DisordersReceptors, GlutamateRNARNA, CircularRNA, Untranslated

Identifiers

PMID25392485
PMCPMC4402329
OpenAlexW2073175342

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.