Evidence map›Paper›PMID 25392417›Full record

ArticleNucleic acids research2015

CeCaFDB: a curated database for the documentation, visualization and comparative analysis of central carbon metabolic flux distributions explored by 13C-fluxomics.

Zhengdong Zhang, Tie Shen, Bin Rui, Wenwei Zhou, Xiangfei Zhou, Chuanyu Shang, Chenwei Xin, Xiaoguang Liu, Gang Li, Jiansi Jiang and 9 more

Abstract read
In one paragraph

Article in Nucleic acids research, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed.

  1. Review
  2. Review
  3. Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Review
  10. Article
  11. WUFlux: an open-source platform forBMC bioinformatics · 2016
    Article
  12. Article
  13. Bioengineering (Basel, Switzerland) · 2015
    Review
  14. Methods and advances in metabolic flux analysis: a mini-review.Journal of industrial microbiology & biotechnology · 2015
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors.

Zhengdong ZhangCollege of Computer Science and Technology, Guizhou University, Guiyang, Guizhou 550025, P.R. China.
Tie ShenKey Laboratory of Information and Computing Science Guizhou Province, Guizhou Normal University, Guiyang, Guizhou 563000, P. R. China.
Bin RuiSchool of Life Sciences, Anhui Agricultural University, Hefei, Anhui 230026, P. R. China.
Wenwei ZhouKey Laboratory of Information and Computing Science Guizhou Province, Guizhou Normal University, Guiyang, Guizhou 563000, P. R. China.
Xiangfei ZhouSchool of Life Sciences, Guizhou Normal University, Guiyang, Guizhou 563000, P. R. China.
Chuanyu ShangSchool of Life Sciences, Guizhou Normal University, Guiyang, Guizhou 563000, P. R. China.
Chenwei XinSchool of Life Sciences, Anhui Agricultural University, Hefei, Anhui 230026, P. R. China.
Xiaoguang LiuKey Laboratory of Information and Computing Science Guizhou Province, Guizhou Normal University, Guiyang, Guizhou 563000, P. R. China.
Gang LiSchool of Life Sciences, Guizhou Normal University, Guiyang, Guizhou 563000, P. R. China.
Jiansi JiangSchool of Life Sciences, Guizhou Normal University, Guiyang, Guizhou 563000, P. R. China.
Chao LiKey Laboratory of Information and Computing Science Guizhou Province, Guizhou Normal University, Guiyang, Guizhou 563000, P. R. China.
Ruiyuan LiSchool of Life Sciences, Guizhou Normal University, Guiyang, Guizhou 563000, P. R. China.
Mengshu HanSchool of Life Sciences, Guizhou Normal University, Guiyang, Guizhou 563000, P. R. China.
Shanping YouSchool of Life Sciences, Guizhou Normal University, Guiyang, Guizhou 563000, P. R. China.
Guojun YuSchool of Life Sciences, Guizhou Normal University, Guiyang, Guizhou 563000, P. R. China.
Yin YiSchool of Life Sciences, Guizhou Normal University, Guiyang, Guizhou 563000, P. R. China.
Han WenSchool of Life Sciences, Anhui Agricultural University, Hefei, Anhui 230026, P. R. China swhx12@ahau.edu.cn.
Zhijie LiuKey Laboratory of Information and Computing Science Guizhou Province, Guizhou Normal University, Guiyang, Guizhou 563000, P. R. China liuzj@gznu.edu.cn.
Xiaoyao XieKey Laboratory of Information and Computing Science Guizhou Province, Guizhou Normal University, Guiyang, Guizhou 563000, P. R. China xyx@gznu.edu.cn.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The Central Carbon Metabolic Flux Database (CeCaFDB, available at http://www.cecafdb.org) is a manually curated, multipurpose and open-access database for the documentation, visualization and comparative analysis of the quantitative flux results of central carbon metabolism among microbes and animal cells. It encompasses records for more than 500 flux distributions among 36 organisms and includes information regarding the genotype, culture medium, growth conditions and other specific information gathered from hundreds of journal articles. In addition to its comprehensive literature-derived data, the CeCaFDB supports a common text search function among the data and interactive visualization of the curated flux distributions with compartmentation information based on the Cytoscape Web API, which facilitates data interpretation. The CeCaFDB offers four modules to calculate a similarity score or to perform an alignment between the flux distributions. One of the modules was built using an inter programming algorithm for flux distribution alignment that was specifically designed for this study. Based on these modules, the CeCaFDB also supports an extensive flux distribution comparison function among the curated data. The CeCaFDB is strenuously designed to address the broad demands of biochemists, metabolic engineers, systems biologists and members of the -omics community.

Indexed as

Databases, ChemicalAnimalsCarbonCarbon IsotopesComputer GraphicsEscherichia coliInternetMethylobacterium extorquensCarbonCarbon Isotopes

Identifiers

PMID25392417
PMCPMC4383945

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.