ReviewJournal of clinical microbiology2015
Standardization of Nucleic Acid Tests for Clinical Measurements of Bacteria and Viruses.
Review in Journal of clinical microbiology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
20 citing papers in PubMed.
- Internationally standardized respiratory viral load testing with limited resources: A derivative-of-care calibration strategy for SARS-CoV-2.Influenza and other respiratory viruses · 2024Article
- Applicability of Control Materials To Support Gene Promoter Characterization and Expression in Engineered Cells Using Digital PCR.Analytical chemistry · 2022Article
- High-accuracy quantitative principle of a new compact digital PCR equipment: Lab On An Array.Genomics & informatics · 2021Article
- Development of a reference standard for the detection and quantification of Mycobacterium avium subsp. paratuberculosis by quantitative PCR.Scientific reports · 2021Article
- Sensitive fluorescence detection of SARS-CoV-2 RNA in clinical samples via one-pot isothermal ligation and transcription.Nature biomedical engineering · 2020Article
- Development of a Nucleic Acid Lateral Flow Immunoassay for the Detection of Human Polyomavirus BK.Diagnostics (Basel, Switzerland) · 2020Article
- Utilization of Digital PCR in Quantity Verification of Plasmid Standards Used in Quantitative PCR.Frontiers in molecular biosciences · 2020Article
- Absolute Quantification of RNA or DNA Using Acid Hydrolysis and Mass Spectrometry.Analytical chemistry · 2019Article
- Advances in Directly Amplifying Nucleic Acids from Complex Samples.Biosensors · 2019Review
- Droplet volume variability as a critical factor for accuracy of absolute quantification using droplet digital PCR.Analytical and bioanalytical chemistry · 2017Article
- Inter-laboratory assessment of different digital PCR platforms for quantification of human cytomegalovirus DNA.Analytical and bioanalytical chemistry · 2017Article
- BK Polyomavirus: Clinical Aspects, Immune Regulation, and Emerging Therapies.Clinical microbiology reviews · 2017Review
- Comparison among the Quantification of Bacterial Pathogens by qPCR, dPCR, and Cultural Methods.Frontiers in microbiology · 2017Article
- A Basic Guide to Real Time PCR in Microbial Diagnostics: Definitions, Parameters, and Everything.Frontiers in microbiology · 2017Review
- The Future of Digital Polymerase Chain Reaction in Virology.Molecular diagnosis & therapy · 2016Review
- Comparison of standard, quantitative and digital PCR in the detection of enterotoxigenic Bacteroides fragilis.Scientific reports · 2016Article
- The use of digital PCR to improve the application of quantitative molecular diagnostic methods for tuberculosis.BMC infectious diseases · 2016Article
- Multicenter Evaluation of Whole-Blood Epstein-Barr Viral Load Standardization Using the WHO International Standard.Journal of clinical microbiology · 2016Article
- Detection of Rare Drug Resistance Mutations by Digital PCR in a Human Influenza A Virus Model System and Clinical Samples.Journal of clinical microbiology · 2016Article
- Assessment of the real-time PCR and different digital PCR platforms for DNA quantification.Analytical and bioanalytical chemistry · 2016Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
13 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Nucleic acid-based tests for infectious diseases currently used in the clinical laboratory and in point-of-care devices are diverse. Measurement challenges associated with standardization of quantitative viral load testing are discussed in relation to human cytomegalovirus, BK virus, and Epstein-Barr virus, while the importance of defining the performance of qualitative methods is illustrated with Mycobacterium tuberculosis and influenza virus. The development of certified reference materials whose values are traceable to higher-order standards and reference measurement procedures, using, for instance, digital PCR, will further contribute to the understanding of analytical performance characteristics and promote clinical data comparability.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.