ArticleInternational journal of colorectal disease2015
Unfavorable effect of small tumor size on cause-specific survival in stage IIA colon cancer, a SEER-based study.
Article in International journal of colorectal disease, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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Who cites it
16 citing papers in PubMed.
- Prognostic impact of tumor size on patients with metastatic colorectal cancer: a large SEER-based retrospective cohort study.Updates in surgery · 2023Trial
- Prognostic Impact of Tumor Size in Patients with Stage T3N1 Colon Cancer.Journal of clinical medicine · 2025Article
- Tumor size in the management of preoperative radiotherapy for locally advanced rectal cancer.Discover oncology · 2025Article
- Association between tumor size and prognosis in patients with small bowel adenocarcinoma-a SEER-based study.Heliyon · 2024Article
- Impact of tumor size on overall survival and cancer-specific survival of early-onset colon and rectal cancer: a retrospective cohort study.International journal of colorectal disease · 2024Article
- The impact of tumor size on the prognosis and chemotherapy efficacy in stage I/II colon cancer patients.Journal of Cancer · 2024Article
- The prognostic role of tumor size in stage T1 gastric cancer.World journal of surgical oncology · 2022Article
- Tumor size improves the accuracy of the prognostic prediction of T4a stage colon cancer.Scientific reports · 2021Article
- Prognostic value of the ratio of carcinoembryonic antigen concentration to maximum tumor diameter in patients with stage II colorectal cancer.Journal of gastrointestinal oncology · 2021Article
- Predictive and Prognostic Effects of Primary Tumor Size on Colorectal Cancer Survival.Frontiers in oncology · 2021Article
- The Critical Role of Tumor Size in Predicting Prognosis for T1 Colon Cancer.The oncologist · 2020Article
- Macroscopic serosal invasion and small tumor size as independent prognostic factors in stage IIA colon cancer.International journal of colorectal disease · 2018Article
- Laparoscopic surgery for locally advanced T4 colon cancer: the long-term outcomes and prognostic factors.Surgery today · 2018Article
- Discordance of pathological thin melanoma thickness and T stage in SEER registry: impacts on clinical management and research directions.Oncotarget · 2017Article
- Smaller tumor size is associated with poor survival in T4b colon cancer.World journal of gastroenterology · 2016Article
- Tumor Deposits and Perineural Invasion had Comparable Impacts on the Survival of Patients With Non-metastatic Colorectal Adenocarcinoma: A Population-Based Propensity Score Matching and Competing Risk Analysis.Cancer control : journal of the Moffitt Cancer CenterArticle
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8 authors.
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Abstract
backgroundWe sought to determine the prognostic role of tumor size on cause-specific survival (CSS) of patients with stage IIA colon cancer.
methodsSurveillance, Epidemiology and End Results (SEER) database was utilized to identify patients with stage IIA colorectal cancer (examined lymph nodes ≥12) diagnosed from 1988 to 2003. The prognostic effect of tumor size on CSS was evaluated by univariate and multivariate analyses.
resultsA total of 8775 patients were enrolled in the analysis. The median follow-up time was 109 months. As determined by minimal P value method, tumor sizes of 2.5 and 6.0 cm were used as optimal cutoff value to divide the cohort. The 8-year CSS of colon cancer with tumor sizes ≤2.5, 2.6-6.0, and >6.0 cm was 81.6, 86.2, and 86.7% respectively (P = 0.003). In the multivariate analysis of colon cancer, using ≤2.5-cm tumors as reference, decreased hazard ratio (HR) of CSS was observed in 2.6-6.0 cm (HR, 0.736; 95% confidence interval (CI), 0.599-0.905; P = 0.004) and >6.0 cm (HR, 0.770; 95% CI, 0.619-0.958; P = 0.019) tumors.
conclusionsIn stage IIA colon cancer, small tumor size represented a subset with decreased CSS. Further studies are merited to validate the unfavorable prognostic role of small tumor size in stage IIA colon cancer.
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