SynthesisBMJ clinical evidence2014
Anal fissure (chronic).
Synthesis in BMJ clinical evidence, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
9 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Efficacy and safety of topical vs. oral calcium channel blockers for chronic anal fissures: a systematic review and meta-analysis.Frontiers in pharmacology · 2025Pooled it
- Pelvic floor physical therapy in the treatment of chronic anal fissure (PAF trial): quality of life outcome.Techniques in coloproctology · 2023Trial
- The Effect of Ostrich Oil on Pain, Healing, and Recurrence of Chronic Anal Fissure: A Randomized Controlled Double-Blind Clinical Trial.Health science reports · 2026Article
- Article
- Laser-based treatment of chronic anal fissures: a report of two cases.Journal of surgical case reports · 2026Article
- Therapy and long-term outcomes of acute anal fissure: a high-volume referral centre experience with 623 patients.Techniques in coloproctology · 2026Article
- Temporal trends and treatment patterns in anal fissure management: insights from a multicenter study in Italy.Techniques in coloproctology · 2024Article
- Safety and efficacy of Levorag emulgel in the treatment of anal fissures using a validated scoring system.Frontiers in surgery · 2023Article
- Pelvic floor physical therapy in the treatment of chronic anal fissure (PAF-study): Study protocol for a randomized controlled trial.Contemporary clinical trials communications · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionAnal fissures are a common cause of anal pain during, and for 1 to 2 hours after, defecation. The cause is not fully understood, but low intake of dietary fibre may be a risk factor. METHODS AND OUTCOMES: We conducted a systematic review and aimed to answer the following clinical question: What are the effects of surgical treatments for chronic anal fissure? We searched: Medline, Embase, The Cochrane Library, and other important databases up to January 2014 (Clinical Evidence reviews are updated periodically; please check our website for the most up-to-date version of this review). We included harms alerts from relevant organisations such as the US Food and Drug Administration (FDA) and the UK Medicines and Healthcare products Regulatory Agency (MHRA).
resultsWe found nine studies that met our inclusion criteria. We performed a GRADE evaluation of the quality of evidence for interventions.
conclusionsIn this systematic review, we present information relating to the effectiveness and safety of the following interventions: anal advancement flap, anal stretch/dilation, and internal anal sphincterotomy.
Indexed as
Identifiers
25391392PMC4229958What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.