Evidence map›Paper›PMID 25389961›Full record

ArticleThe journal of nutrition, health & aging2014

Inverse association between dietary habits with high total antioxidant capacity and prevalence of frailty among elderly Japanese women: a multicenter cross-sectional study.

S Kobayashi, K Asakura, H Suga, S Sasaki, Three-generation Study of Women on Diets and Health Study Groups

Registry-linked trialAbstract readMulticenter Study
PubMed Full text at PMC Publisher
In one paragraph

Article in The journal of nutrition, health & aging, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02753582 (The Effect of Superoxide Dismutase), which is not on this map. Cited by 40 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
40citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02753582 phase4unknown statusnot on this mapstarted 2016, after this paper: background citation

The Effect of Superoxide Dismutase (SOD) Enzyme on Frailty and Health Related Quality of Life Among Indonesian Pre-frail Elderly: A Double Blind Randomized Controlled Trial

TypeinterventionalSponsorIndonesia UniversityRan2016 to 2017Enrolled150ConditionsPre-frail ElderlyArmsSOD+Gliadin Capsule, Placebo
3 · Its place in the literature

Who cites it

40 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Fruit and Vegetable Consumption and Frailty: A Systematic Review.The journal of nutrition, health & aging · 2018
    Pooled it
  2. Pooled it
  3. Trial
  4. Article
  5. Article
  6. Article
  7. Article
  8. Lifestyle Interventions in Frailty.Advances in experimental medicine and biology · 2025
    Review
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Review
  15. Article
  16. Estimate of Dietary Total Antioxidant Capacity of Pregnant Women and Associated Factors.Revista brasileira de ginecologia e obstetricia : revista da Federacao Brasileira das Sociedades de Ginecologia e Obstetricia · 2022
    Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

S KobayashiS. Sasaki, Department of Social and Preventive Epidemiology, School of Public Health, the University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-0033, Japan; E-mail: stssasak@m.u-tokyo.ac.jp; Tel: +81-3-5841-7872; Fax: +81-3-5841-7873.
K Asakura
H Suga
S Sasaki
Three-generation Study of Women on Diets and Health Study Groups

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo examine the association of dietary habits with high total antioxidant capacity (TAC) with frailty among elderly Japanese women.

designCross-sectional multicenter study.

settingThirty-five of 47 prefectures in Japan.

participants2121 grandmothers or acquaintances of dietetic students aged 65 and older. MEASUREMENTS: Dietary TAC and food intakes were calculated using a validated brief-type self-administered diet history questionnaire. The TAC value of each food was assigned using four different assays, ferric reducing ability of plasma (FRAP), oxygen radical absorbance capacity (ORAC), Trolox equivalent antioxidant capacity (TEAC), and total radical-trapping antioxidant parameter (TRAP). Frailty was defined as the presence three or more of the following four components: slowness and weakness (two points), exhaustion, low physical activity, and unintentional weight loss.

resultsThe number of subjects with frailty was 486 (23%). Multivariate adjusted ORs (95% CI) for frailty in the highest compared to the lowest quintile were 0.35 (0.24, 0.53) for FRAP, 0.35 (0.23, 0.52) for ORAC, 0.40 (0.27, 0.60) for TEAC, and 0.41 (0.28, 0.62) for TRAP. The intakes of green tea, coffee, vegetables, and fruits which contribute to dietary TAC were also associated with lower odds of frailty (the range of multivariate adjusted OR: 0.47 for vegetables to 0.77 for green tea), although the odds ratios were less marked than those of dietary TAC.

conclusionsDietary habits with high TAC showed a stronger inverse association with frailty in elderly Japanese women than the individual foods examined.

Indexed as

DietAgedAged, 80 and overAntioxidantsCoffeeCross-Sectional StudiesDieteticsFatigueFeeding BehaviorFemaleFood AnalysisFrail ElderlyFruitHumansJapanPrevalenceAntioxidantsCoffeeTea

Identifiers

PMID25389961
PMCPMC12878508

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.