Evidence map›Paper›PMID 25389898›Full record

ArticleNutrients2014

Dietary flavonoids and gastric cancer risk in a Korean population.

Hae Dong Woo, Jeonghee Lee, Il Ju Choi, Chan Gyoo Kim, Jong Yeul Lee, Oran Kwon, Jeongseon Kim

Open access · goldAbstract read
In one paragraph

Article in Nutrients, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 56 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
56citing papers in PubMed, 5 pooled it
11.8field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

56 citing papers in PubMed, 5 syntheses or guidelines pooled it, 89 citations in OpenAlex.

  1. Pooled it
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  3. Helicobacter pylori Infection and Risk of Gastric Cancer in Korea: A Quantitative Systematic Review.Journal of preventive medicine and public health = Yebang Uihakhoe chi · 2016
    Pooled it
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  6. Review
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  12. Article
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  16. Evidence of Flavonoids on Disease Prevention.Antioxidants (Basel, Switzerland) · 2023
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 2 countries.

Hae Dong WooMolecular Epidemiology Branch, Division of Cancer Epidemiology and Prevention, Research Institute, National Cancer Center, Gyeonggi-do 410-769, Korea. hdwoo@ncc.re.kr.
Jeonghee LeeMolecular Epidemiology Branch, Division of Cancer Epidemiology and Prevention, Research Institute, National Cancer Center, Gyeonggi-do 410-769, Korea. jeonghee@ncc.re.kr.
Il Ju ChoiCenter for Gastric Cancer, National Cancer Center Hospital, National Cancer Center, Gyeonggi-do 410-769, Korea. cij1224@ncc.re.kr.
Chan Gyoo KimCenter for Gastric Cancer, National Cancer Center Hospital, National Cancer Center, Gyeonggi-do 410-769, Korea. glse@ncc.re.kr.
Jong Yeul LeeCenter for Gastric Cancer, National Cancer Center Hospital, National Cancer Center, Gyeonggi-do 410-769, Korea. jylee@ncc.re.kr.
Oran KwonDepartment of Nutritional Science and Food Management, Ewha Womans University, Seoul 120-750, Korea. orank@ewha.ac.kr.
Jeongseon KimMolecular Epidemiology Branch, Division of Cancer Epidemiology and Prevention, Research Institute, National Cancer Center, Gyeonggi-do 410-769, Korea. jskim@ncc.re.kr.
National Cancer Center · USNational Cancer Center · KREwha Womans University · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Gastric cancer is the most common cancer among men in Korea, and dietary factors are closely associated with gastric cancer risk. We performed a case-control study using 334 cases and 334 matched controls aged 35-75 years. Significant associations were observed in total dietary flavonoids and their subclasses, with the exception of anthocyanidins and isoflavones (OR (95% CI): 0.49 (0.31-0.76), p trend = 0.007 for total flavonoids). However, these associations were not significant after further adjustment for fruits and vegetable consumption (OR (95% CI): 0.62 (0.36-1.09), p trend = 0.458 for total flavonoids). Total flavonoids and their subclasses, except for isoflavones, were significantly associated with a reduced risk gastric cancer in women (OR (95% CI): 0.33 (0.15-0.73), p trend = 0.001 for total flavonoids) but not in men (OR (95% CI): 0.70 (0.39-1.24), p trend = 0.393 for total flavonoids). A significant inverse association with gastric cancer risk was observed in flavones, even after additional adjustment for fruits and vegetable consumption in women. No significantly different effects of flavonoids were observed between H. pylori-positive and negative subjects. In conclusion, dietary flavonoids were inversely associated with gastric cancer risk, and these protective effects of dietary flavonoids were prominent in women. No clear differences were observed in the subgroup analysis of H. pylori and smoking status.

Indexed as

Asian PeopleAdultAgedAnthocyaninsCase-Control StudiesFemaleFlavonoidsFruitHelicobacter InfectionsHelicobacter pyloriHumansIsoflavonesLogistic ModelsMaleMiddle AgedMotor ActivityAnthocyaninsFlavonoidsIsoflavonesPolyphenols

Identifiers

PMID25389898
PMCPMC4245574
OpenAlexW1993846064

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.