ArticleMolecules (Basel, Switzerland)2014
Chemical compositions, chromatographic fingerprints and antioxidant activities of Andrographis Herba.
Article in Molecules (Basel, Switzerland), 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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Who cites it
12 citing papers in PubMed, 37 citations in OpenAlex.
- Sustainable management of soil-borne disease: integrating fumigation with Andrographis paniculata residues to rebuild rhizosphere function.BMC microbiology · 2025Article
- Pharmacological Effects and Pharmacokinetic Profiles of Dehydroandrographolide.Mediators of inflammation · 2025Review
- Enhancing oral bioavailability of andrographolide using solubilizing agents and bioenhancer: comparative pharmacokinetics ofPharmaceutical biology · 2024Article
- Characterization of the volatile components in the processing ofFood science & nutrition · 2024Article
- Assessment of the Phytochemical Profile, Antioxidant Capacity, and Hepatoprotective Effect ofMedicina (Kaunas, Lithuania) · 2023Article
- Network pharmacology analysis and experimental validation to explore the mechanism of Bushao Tiaozhi capsule (BSTZC) on hyperlipidemia.Scientific reports · 2022Article
- Classification of Andrographis paniculata extracts by solvent extraction using HPLC fingerprint and chemometric analysis.BMC research notes · 2020Article
- Andrographolide, a Natural Antioxidant: An Update.Antioxidants (Basel, Switzerland) · 2019Review
- Protective effect of dehydroandrographolide on obstructive cholestasis in bile duct-ligated mice.Oncotarget · 2017Article
- Quality Control of the Root and Rhizome of Helminthostachys zeylanica (Daodi-Ugon) by HPLC Using Quercetin and Ugonins as Markers.Molecules (Basel, Switzerland) · 2017Article
- Multi-Dimensional Spectrum-Effect Relationship of the Impact of Chinese Herbal Formula Lichong Shengsui Yin on Ovarian Cancer.Molecules (Basel, Switzerland) · 2017Article
- Phytochemical analysis of Pathyashadangam kwath and its standardization by HPLC and HPTLC.Journal of Ayurveda and integrative medicineArticle
Corrections and comments
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Authors and funding
6 authors at 4 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
This paper describes the development of an HPLC-UV-MS method for quantitative determination of andrographolide and dehydroandrographolide in Andrographis Herba and establishment of its chromatographic fingerprint. The method was validated for linearity, limit of detection and quantification, inter- and intra-day precisions, repeatability, stability and recovery. All the validation results of quantitative determination and fingerprinting methods were satisfactory. The developed method was then applied to assay the contents of andrographolide and dehydroandrographolide and to acquire the fingerprints of all the collected Andrographis Herba samples. Furthermore, similarity analysis and principal component analysis were used to reveal the similarities and differences between the samples on the basis of the characteristic peaks. More importantly, the DPPH free radical-scavenging and ferric reducing capacities of the Andrographis Herba samples were assayed. By bivariate correlation analysis, we found that six compounds are positively correlated to DPPH free radical scavenging and ferric reducing capacities, and four compounds are negatively correlated to DPPH free radical scavenging and ferric reducing capacities.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.