Evidence map›Paper›PMID 25389384›Full record

ReviewFrontiers in neuroscience2014

Epigenetic changes in the estrogen receptor α gene promoter: implications in sociosexual behaviors.

Ken Ichi Matsuda

Open access · goldAbstract readReview
In one paragraph

Review in Frontiers in neuroscience, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
1.7field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 24 citations in OpenAlex.

  1. Article
  2. Effect of adverse childhood experiences and DNA methylation on male sexual orientation.Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences · 2021
    Article
  3. Article
  4. Sleep and Methylation of Estrogen Receptor Genes,Nature and science of sleep · 2020
    Article
  5. Article
  6. Is Sexual Differentiation of Brain and Behavior Epigenetic?Current opinion in behavioral sciences · 2019
    Article
  7. Article
  8. Androgen and estrogen sensitivity of bird song: a comparative view on gene regulatory levels.Journal of comparative physiology. A, Neuroethology, sensory, neural, and behavioral physiology · 2018
    Review
  9. Epigenetic impacts of endocrine disruptors in the brain.Frontiers in neuroendocrinology · 2017
    Review
  10. The epigenetic regulation of HIF-1α by SIRT1 in MPP(+) treated SH-SY5Y cells.Biochemical and biophysical research communications · 2016
    Article
  11. Review
  12. Review
  13. Review
  14. At the frontier of epigenetics of brain sex differences.Frontiers in behavioral neuroscience · 2015
    Review
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author at 1 institution in 1 country.

Ken Ichi MatsudaDepartment of Anatomy and Neurobiology, Graduate School of Medical Science, Kyoto Prefectural University of Medicine Kyoto, Japan.
Kyoto Prefectural University of Medicine · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Estrogen action through estrogen receptor α (ERα) is involved in the control of sexual and social behaviors in adult mammals. Alteration of ERα gene activity mediated by epigenetic mechanisms, such as histone modifications and DNA methylation, in particular brain areas appears to be crucial for determining the extents of these behaviors between the sexes and among individuals within the same sex. This review provides a summary of the epigenetic changes in the ERα gene promoter that correlate with sociosexual behaviors.

Indexed as

DNA methylationepigeneticsestrogen receptor αhistone acetylationhistone deacetylationsexual behaviorsexual differentiationsociosexual behavior

Identifiers

PMID25389384
PMCPMC4211403
OpenAlexW2052772134

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.