Evidence map›Paper›PMID 25389275›Full record

ArticleEnvironmental health perspectives2015

A longitudinal cohort study of body mass index and childhood exposure to secondhand tobacco smoke and air pollution: the Southern California Children's Health Study.

Rob McConnell, Ernest Shen, Frank D Gilliland, Michael Jerrett, Jennifer Wolch, Chih-Chieh Chang, Frederick Lurmann, Kiros Berhane

Erratum issuedOpen access · diamondAbstract read
In one paragraph

Article in Environmental health perspectives, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 114 papers, 6 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
114citing papers in PubMed, 6 pooled it
14.8field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

114 citing papers in PubMed, 6 syntheses or guidelines pooled it, 183 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. The built environment as determinant of childhood obesity: A systematic literature review.Obesity reviews : an official journal of the International Association for the Study of Obesity · 2022
    Pooled it
  4. Traffic-related environmental factors and childhood obesity: A systematic review and meta-analysis.Obesity reviews : an official journal of the International Association for the Study of Obesity · 2021
    Pooled it
  5. Pooled it
  6. Impact of ambient air pollution on obesity: a systematic review.International journal of obesity (2005) · 2018
    Pooled it
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Review
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article

54 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 1 country.

Rob McConnellDepartment of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, California, USA.
Ernest Shen
Frank D Gilliland
Michael Jerrett
Jennifer Wolch
Chih-Chieh Chang
Frederick Lurmann
Kiros Berhane
University of Southern California · USBerkeley Public Health Division · USSonoma Technology (United States) · USUniversity of California, Berkeley · US

Funding

Translational Research Support CoreP30ES007048 · NIEHS · UNIVERSITY OF SOUTHERN CALIFORNIA · PI ROB S MCCONNELL · 1996 to 2026
$46.4M
Urban Air Pollution and Children's Respiratory HealthP01ES011627 · NIEHS · UNIVERSITY OF SOUTHERN CALIFORNIA · PI GILLILAND, FRANK D. · 2002 to 2011
$30.2M
USC Tobacco Center of Regulatory Science (TCORS) for Vulnerable PopulationsP50CA180905 · NCI · UNIVERSITY OF SOUTHERN CALIFORNIA · PI PENTZ, MARY ANN, SAMET, JONATHAN M · 2013 to 2017
$20.1M
Urban Air Pollution &Persistent Early Life AsthmaP01ES009581 · NIEHS · UNIVERSITY OF SOUTHERN CALIFORNIA · PI GILLILAND, FRANK D. · 1999 to 2010
$6.8M
Southern California Children's Environmental Health Center (SC-CEHC)P01ES022845 · NIEHS · UNIVERSITY OF SOUTHERN CALIFORNIA · PI HRICKO, ANDREA M · 2013 to 2018
$4.0M
Childhood Asthma, Susceptibility and Biological Activity of Ambient ParticlesR01ES016535 · NIEHS · UNIVERSITY OF SOUTHERN CALIFORNIA · PI MCCONNELL, ROB S · 2008 to 2011
$2.0M
FLEXIBLE MULTI-LEVEL MODELS FOR LONGITUDINAL ANALYSIS OF CHILDHOOD OBESITYR01HD061968 · NICHD · UNIVERSITY OF SOUTHERN CALIFORNIA · PI BERHANE, KIROS T · 2011 to 2013
$1.1M
Air pollution, immune modulation of adipose tissue and type-2 diabetes risk factorsR21ES024707 · NIEHS · UNIVERSITY OF SOUTHERN CALIFORNIA · PI AKBARI, OMID, MCCONNELL, ROB S · 2014 to 2015
$453k
Socioeconomic Status, Stress, Air Pollution and AsthmaR03ES014046 · NIEHS · UNIVERSITY OF SOUTHERN CALIFORNIA · PI MCCONNELL, ROB S · 2005 to 2006
$161k
NCI NIH HHS P50 CA180905NICHD NIH HHS R01 HD061968NICHD NIH HHS R01HD061968NIEHS NIH HHS P01 ES009581NIEHS NIH HHS P01ES009581NIEHS NIH HHS P01 ES011627NIEHS NIH HHS P01ES011627NIEHS NIH HHS P01 ES022845NIEHS NIH HHS P01ES022845NIEHS NIH HHS P30 ES007048NIEHS NIH HHS P30ES007048NIEHS NIH HHS R01 ES016535NIEHS NIH HHS R01ES016535NIEHS NIH HHS R03 ES014046NIEHS NIH HHS R03ES014046NIEHS NIH HHS R21 ES024707
6 · The paper itself

Abstract

backgroundChildhood body mass index (BMI) and obesity prevalence have been associated with exposure to secondhand smoke (SHS), maternal smoking during pregnancy, and vehicular air pollution. There has been little previous study of joint BMI effects of air pollution and tobacco smoke exposure.

methodsInformation on exposure to SHS and maternal smoking during pregnancy was collected on 3,318 participants at enrollment into the Southern California Children's Health Study. At study entry at average age of 10 years, residential near-roadway pollution exposure (NRP) was estimated based on a line source dispersion model accounting for traffic volume, proximity, and meteorology. Lifetime exposure to tobacco smoke was assessed by parent questionnaire. Associations with subsequent BMI growth trajectory based on annual measurements and attained BMI at 18 years of age were assessed using a multilevel modeling strategy.

resultsMaternal smoking during pregnancy was associated with estimated BMI growth over 8-year follow-up (0.72 kg/m2 higher; 95% CI: 0.14, 1.31) and attained BMI (1.14 kg/m2 higher; 95% CI: 0.66, 1.62). SHS exposure before enrollment was positively associated with BMI growth (0.81 kg/m2 higher; 95% CI: 0.36, 1.27) and attained BMI (1.23 kg/m2 higher; 95% CI: 0.86, 1.61). Growth and attained BMI increased with more smokers in the home. Compared with children without a history of SHS and NRP below the median, attained BMI was 0.80 kg/m2 higher (95% CI: 0.27, 1.32) with exposure to high NRP without SHS; 0.85 kg/m2 higher (95% CI: 0.43, 1.28) with low NRP and a history of SHS; and 2.15 kg/m2 higher (95% CI: 1.52, 2.77) with high NRP and a history of SHS (interaction p-value 0.007). These results suggest a synergistic effect.

conclusionsOur findings strengthen emerging evidence that exposure to tobacco smoke and NRP contribute to development of childhood obesity and suggest that combined exposures may have synergistic effects.

Indexed as

Body Mass IndexAdolescentAir PollutantsAir PollutionCaliforniaChildEnvironmental ExposureFemaleHumansLongitudinal StudiesMaleMaternal ExposurePregnancySmokingTobacco Smoke PollutionVehicle EmissionsAir PollutantsTobacco Smoke PollutionVehicle Emissions

Identifiers

PMID25389275
PMCPMC4384197
OpenAlexW1984564994

What OpenQuestion holds

Textmetadata
LicenceCC0
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.