Evidence map›Paper›PMID 25388883›Full record

Observational studyThe British journal of surgery2014

Development and validation of the Surgical Outcome Risk Tool (SORT).

K L Protopapa, J C Simpson, N C E Smith, S R Moonesinghe

2 registry-linked trialsAbstract readMulticenter StudyObservational StudyValidation Study
In one paragraph

Observational study in The British journal of surgery, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 113 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
113citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04041076 unknown statusnot on this mapstarted 2019, after this paper: background citation

Validation of Postoperative Mortality Prediction for Elective Major Surgical Operation With Existing Risk Calculators Based on Preoperative Parameters

TypeobservationalSponsorChinese University of Hong KongRan2019 to 2020Enrolled5,000ConditionsSurgery, DeathArmsMajor surgical operation
NCT07293377 completednot on this mapstarted 2022, after this paper: background citation

Prospective Validation of a Risk Stratification Model for Mortality Up to 30 Days After Surgery

Typeobservational_patient_registrySponsorHospital Nossa Senhora da ConceicaoRan2022 to 2025Enrolled3,000ConditionsPostoperative Complications
3 · Its place in the literature

Who cites it

113 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Guideline
  2. Pooled it
  3. Waterlow score for risk assessment in surgical patients: a systematic review.Annals of the Royal College of Surgeons of England · 2021
    Pooled it
  4. Trial
  5. Article
  6. Article
  7. Article
  8. Review
  9. Observational
  10. Article
  11. Article
  12. 30-Day mortality risk predictors for emergency laparotomy: a comparative study.Annals of the Royal College of Surgeons of England · 2026
    Article
  13. Observational
  14. Article
  15. Article
  16. Observational
  17. Article
  18. Article
  19. Article
  20. Article

53 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

K L ProtopapaNational Confidential Enquiry into Patient Outcome and Death (NCEPOD), London, UK.
J C Simpson
N C E Smith
S R Moonesinghe

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundExisting risk stratification tools have limitations and clinical experience suggests they are not used routinely. The aim of this study was to develop and validate a preoperative risk stratification tool to predict 30-day mortality after non-cardiac surgery in adults by analysis of data from the observational National Confidential Enquiry into Patient Outcome and Death (NCEPOD) Knowing the Risk study.

methodsThe data set was split into derivation and validation cohorts. Logistic regression was used to construct a model in the derivation cohort to create the Surgical Outcome Risk Tool (SORT), which was tested in the validation cohort.

resultsProspective data for 19 097 cases in 326 hospitals were obtained from the NCEPOD study. Following exclusion of 2309, details of 16 788 patients were analysed (derivation cohort 11 219, validation cohort 5569). A model of 45 risk factors was refined on repeated regression analyses to develop a model comprising six variables: American Society of Anesthesiologists Physical Status (ASA-PS) grade, urgency of surgery (expedited, urgent, immediate), high-risk surgical specialty (gastrointestinal, thoracic, vascular), surgical severity (from minor to complex major), cancer and age 65 years or over. In the validation cohort, the SORT was well calibrated and demonstrated better discrimination than the ASA-PS and Surgical Risk Scale; areas under the receiver operating characteristic (ROC) curve were 0·91 (95 per cent c.i. 0·88 to 0·94), 0·87 (0·84 to 0·91) and 0·88 (0·84 to 0·92) respectively (P < 0·001).

conclusionThe SORT allows rapid and simple data entry of six preoperative variables, and provides a percentage mortality risk for individuals undergoing surgery.

Indexed as

AdolescentAdultAgedAged, 80 and overFemaleHumansMaleMiddle AgedPostoperative ComplicationsProspective StudiesRisk AssessmentROC CurveSurgical Procedures, OperativeYoung Adult

Identifiers

PMID25388883
PMCPMC4240514

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.