Evidence map›Paper›PMID 25388686›Full record

ArticleSao Paulo medical journal = Revista paulista de medicina

Patients' perceptions about diagnosis and treatment of chronic myeloid leukemia: a cross-sectional study among Brazilian patients.

Nelson Hamerschlak, Carmino de Souza, Ana Lúcia Cornacchioni, Ricardo Pasquini, Daniel Tabak, Nelson Spector, Merula Steagall

Abstract read
In one paragraph

Article in Sao Paulo medical journal = Revista paulista de medicina. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Nelson HamerschlakBone Marrow Transplantation Unit, Hospital Israelita Albert Einstein, São Paulo, Brazil.
Carmino de SouzaInternal Medicine, Universidade Estadual de Campinas (Unicamp), São Paulo, Brazil.
Ana Lúcia CornacchioniInstituto de Tratamento do Câncer Infantil, São Paulo, Brazil.
Ricardo PasquiniInternal Medicine, Universidade Federal do Paraná, São Paulo, Brazil.
Daniel TabakCentro de Tratamento Oncológico, São Paulo, Brazil.
Nelson SpectorUniversidade Federal do Rio de Janeiro, Rio de Janeiro, Brazil.
Merula SteagallAssociação Brasileira de Linfoma e Leucemia, São Paulo, Brazil.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

CONTEXT AND

objectivesChronic myeloid leukemia (CML) requires strict daily compliance with oral medication and regular blood and bone marrow control tests. The objective was to evaluate CML patients' perceptions about the disease, their access to information regarding the diagnosis, monitoring and treatment, adverse effects and associations of these variables with patients' demographics, region and healthcare access. DESIGN AND

settingProspective cross-sectional study among CML patients registered with the Brazilian Lymphoma and Leukemia Association (ABRALE).

methodsCML patients receiving treatment through the public healthcare system were interviewed by telephone.

resultsAmong 1,102 patients interviewed, the symptoms most frequently leading them to seek medical care were weakness or fatigue. One third were diagnosed by means of routine tests. The time that elapsed between first symptoms and seeking medical care was 42.28 ± 154.21 days. Most patients had been tested at least once for Philadelphia chromosome, but 43.2% did not know the results. 64.8% had had polymerase chain reaction testing for the BCR/ABL gene every three months. 47% believed that CML could be controlled, but 33.1% believed that there was no treatment. About 24% reported occasionally stopping their medication. Imatinib was associated with nausea, cramps and muscle pain. Self-reported treatment adherence was significantly associated with normalized blood count, and positively associated with imatinib.

conclusionsThere is a lack of information or understanding about disease monitoring tools among Brazilian CML patients; they are diagnosed quickly and have good access to treatment. Correct comprehension of CML control tools is impaired in Brazilian patients.

Indexed as

Health Knowledge, Attitudes, PracticeAdolescentAdultAgedAged, 80 and overAntineoplastic AgentsBrazilChildChild, PreschoolCross-Sectional StudiesFemaleHealth Services AccessibilityHumansImatinib MesylateLeukemia, Myelogenous, Chronic, BCR-ABL PositiveMaleAntineoplastic AgentsImatinib Mesylate

Identifiers

PMID25388686
PMCPMC10496560

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.