ArticleBMC infectious diseases2014
Keratitis by Fusarium temperatum, a novel opportunist.
Article in BMC infectious diseases, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.
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Who cites it
19 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Fusarium Keratitis: A Systematic Review (1969 to 2023).Mycopathologia · 2024Pooled it
- Integrated on-site detection of Fusarium temperatum based on a droplet digital CRISPR-based platform.Mikrochimica acta · 2026Article
- qPCR-Based Molecular Detection of Trichophyton indotineae by Targeting Divergent Sequences.Mycopathologia · 2025Article
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- Fungal burn wound infection caused byAnnals of medicine and surgery (2012) · 2021Article
- Development and Analysis of qPCR for the Identification of Arthroconidial Yeasts of the Genus Magnusiomyces.Mycopathologia · 2021Article
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- Evaluation of Microsatellite Typing, ITS Sequencing, AFLP Fingerprinting, MALDI-TOF MS, and Fourier-Transform Infrared Spectroscopy Analysis ofJournal of fungi (Basel, Switzerland) · 2020Article
- MultiresistantInfection and drug resistance · 2019Review
- Fungal Planet description sheets: 951-1041.Persoonia · 2019Article
- Molecular Characterization and Antifungal Susceptibility of ClinicalFrontiers in microbiology · 2019Article
- Mycotic Keratitis Caused by Fusarium solani sensu stricto (FSSC5): A Case Series.Mycopathologia · 2018Article
- Global Molecular Diversity of the Halotolerant FungusLife (Basel, Switzerland) · 2018Article
- Phylogenetic Diversity and In Vitro Susceptibility Profiles of Human Pathogenic Members of the Fusarium fujikuroi Species Complex Isolated from South India.Mycopathologia · 2018Article
- Molecular Diagnostics of Arthroconidial Yeasts, Frequent Pulmonary Opportunists.Journal of clinical microbiology · 2018Article
- Reduced Multidrug Susceptibility Profile Is a Common Feature of Opportunistic Fusarium Species: Fusarium Multi-Drug Resistant Pattern.Journal of fungi (Basel, Switzerland) · 2017Review
- Article
- Diagnosis ofCurrent fungal infection reportsReview
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7 authors.
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No grant is acknowledged in the PubMed record.
Abstract
backgroundFusarium species are among the most common fungi present in the environment and some species have emerged as major opportunistic fungal infection in human. However, in immunocompromised hosts they can be virulent pathogens and can cause death. The pathogenesis of this infection relies on three factors: colonization, tissue damage, and immunosuppression. A novel Fusarium species is reported for the first time from keratitis in an agriculture worker who acquired the infection from plant material of maize. Maize plants are the natural host of this fungus where it causes stalk rot and seeding malformation under temperate and humid climatic conditions. The clinical manifestation, microbiological morphology, physiological features and molecular data are described.
methodsDiagnosis was established by using polymerase chain reaction of fungal DNA followed by sequencing portions of translation elongation factor 1 alpha (TEF1 α) and beta-tubulin (BT2) genes. Susceptibility profiles of this fungus were evaluated using CLSI broth microdilution method.
resultsThe analyses of these two genes sequences support a novel opportunist with the designation Fusarium temperatum. Phylogenetic analyses showed that the reported clinical isolate was nested within the Fusarium fujikuroi species complex. Antifungal susceptibility testing demonstrated that the fungus had low MICs of micafungin (0.031 μg/ml), posaconazole (0.25 μg/ml) and amphotericin B (0.5 μg/ml).
conclusionThe present case extends the significance of the genus Fusarium as agents of keratitis and underscores the utility of molecular verification of these emerging fungi in the human host.
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