ArticlePsychophysiology2014
Heritability and molecular genetic basis of antisaccade eye tracking error rate: a genome-wide association study.
Article in Psychophysiology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
19 citing papers in PubMed, 1 synthesis or guideline pooled it, 26 citations in OpenAlex.
- Transdiagnostic eye-tracking biomarkers of inattention across psychiatric disorders: a systematic review.BMC psychiatry · 2025Pooled it
- Blink-induced changes in pupil dynamics are consistent and heritable.Scientific reports · 2024Article
- Positive and Negative Symptoms Are Associated with Distinct Effects on Predictive Saccades.Brain sciences · 2022Article
- Volitional eye movement control and ADHD traits: a twin study.Journal of child psychology and psychiatry, and allied disciplines · 2020Article
- Parental warmth interacts with several genes to affect executive function components: a genome-wide environment interaction study.BMC genetics · 2020Article
- The utility of twins in developmental cognitive neuroscience research: How twins strengthen the ABCD research design.Developmental cognitive neuroscience · 2018Review
- Impaired Antisaccades in Obsessive-Compulsive Disorder: Evidence From Meta-Analysis and a Large Empirical Study.Frontiers in psychiatry · 2018Article
- Genome-wide association studies of smooth pursuit and antisaccade eye movements in psychotic disorders: findings from the B-SNIP study.Translational psychiatry · 2017Article
- What can time-frequency and phase coherence measures tell us about the genetic basis of P3 amplitude?International journal of psychophysiology : official journal of the International Organization of Psychophysiology · 2017Article
- Psychophysiological endophenotypes to characterize mechanisms of known schizophrenia genetic loci.Psychological medicine · 2017Article
- Endophenotype best practices.International journal of psychophysiology : official journal of the International Organization of Psychophysiology · 2017Review
- Longitudinal stability and predictive utility of the visual P3 response in adults with externalizing psychopathology.Psychophysiology · 2015Article
- Common genetic variation and schizophrenia polygenic risk influence neurocognitive performance in young adulthood.American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics · 2015Article
- Genetic associations of nonsynonymous exonic variants with psychophysiological endophenotypes.Psychophysiology · 2014Article
- In search of rare variants: preliminary results from whole genome sequencing of 1,325 individuals with psychophysiological endophenotypes.Psychophysiology · 2014Article
- Genome-wide scans of genetic variants for psychophysiological endophenotypes: a methodological overview.Psychophysiology · 2014Review
- The Power of Theory, Research Design, and Transdisciplinary Integration in Moving Psychopathology Forward.Psychological inquiryArticle
- Electrophysiological Endophenotypes for Schizophrenia.Harvard review of psychiatryReview
- Genetic and environmental contributions to individual differences in visual attention and oculomotor control in early infancy.Child developmentArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 1 institution in 1 country.
Funding
Abstract
Antisaccade deficits reflect abnormalities in executive function linked to various disorders including schizophrenia, externalizing psychopathology, and neurological conditions. We examined the genetic bases of antisaccade error in a sample of community-based twins and parents (N = 4,469). Biometric models showed that about half of the variance in the antisaccade response was due to genetic factors and half due to nonshared environmental factors. Molecular genetic analyses supported these results, showing that the heritability accounted for by common molecular genetic variants approximated biometric estimates. Genome-wide analyses revealed several SNPs as well as two genes-B3GNT7 and NCL-on Chromosome 2 associated with antisaccade error. SNPs and genes hypothesized to be associated with antisaccade error based on prior work, although generating some suggestive findings for MIR137, GRM8, and CACNG2, could not be confirmed.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.