ArticlePsychophysiology2014
Heritability and molecular-genetic basis of resting EEG activity: a genome-wide association study.
Article in Psychophysiology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
27 citing papers in PubMed.
- Reduced occurrence of alpha waves during resting state predicts high attention-deficit/hyperactivity disorder traits in young adults.JCPP advances · 2026Article
- ADHD polygenic risk predicts neural signatures of cognitive control: Evidence from midfrontal theta dynamics.Translational psychiatry · 2026Article
- Depression and anxiety are increased in autism and ADHD: Evidence from a young adult community-based sample.JCPP advances · 2025Article
- Face processing in young adults with autism and ADHD: An event related potentials study.Frontiers in psychiatry · 2023Article
- Quality of life, functional impairment and continuous performance task event-related potentials (ERPs) in young adults with ADHD and autism: A twin study.JCPP advances · 2022Article
- Article
- Large-scale collaboration in ENIGMA-EEG: A perspective on the meta-analytic approach to link neurological and psychiatric liability genes to electrophysiological brain activity.Brain and behavior · 2021Article
- Genome-Wide Scan for Five Brain Oscillatory Phenotypes Identifies a New QTL Associated with Theta EEG Band.Brain sciences · 2020Article
- Human brain arousal in the resting state: a genome-wide association study.Molecular psychiatry · 2019Article
- Discovering heritable modes of MEG spectral power.Human brain mapping · 2019Article
- Genome-wide association analysis links multiple psychiatric liability genes to oscillatory brain activity.Human brain mapping · 2018Article
- Heritability of Sleep EEG Topography in Adolescence: Results from a Longitudinal Twin Study.Scientific reports · 2018Article
- An endophenotype approach to the genetics of alcohol dependence: a genome wide association study of fast beta EEG in families of African ancestry.Molecular psychiatry · 2017Article
- Whole genome sequence association and ancestry-informed polygenic profile of EEG alpha in a Native American population.American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics · 2017Article
- What can time-frequency and phase coherence measures tell us about the genetic basis of P3 amplitude?International journal of psychophysiology : official journal of the International Organization of Psychophysiology · 2017Article
- A genome wide association study of fast beta EEG in families of European ancestry.International journal of psychophysiology : official journal of the International Organization of Psychophysiology · 2017Article
- Psychophysiological endophenotypes to characterize mechanisms of known schizophrenia genetic loci.Psychological medicine · 2017Article
- One-year developmental stability and covariance among oddball, novelty, go/no-go, and flanker event-related potentials in adolescence: A monozygotic twin study.Psychophysiology · 2016Article
- Cracking the brain's genetic code.Proceedings of the National Academy of Sciences of the United States of America · 2015Article
- Longitudinal stability and predictive utility of the visual P3 response in adults with externalizing psychopathology.Psychophysiology · 2015Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
Abstract
Several EEG parameters are potential endophenotypes for different psychiatric disorders. The present study consists of a comprehensive behavioral- and molecular-genetic analysis of such parameters in a large community sample (N = 4,026) of adolescent twins and their parents, genotyped for 527,829 single nucleotide polymorphisms (SNPs). Biometric heritability estimates ranged from .49 to .85, with a median of .78. The additive effect of all SNPs (SNP heritability) varied across electrodes. Although individual SNPs were not significantly associated with EEG parameters, several genes were associated with delta power. We also obtained an association between the GABRA2 gene and beta power (p < .014), consistent with findings reported by others, although this did not survive Bonferroni correction. If EEG parameters conform to a largely polygenic model of inheritance, larger sample sizes will be required to detect individual variants reliably.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.