ArticleAnais brasileiros de dermatologia
Phototherapy promotes healing of cutaneous wounds in undernourished rats.
Article in Anais brasileiros de dermatologia. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.
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Who cites it
9 citing papers in PubMed, 1 synthesis or guideline pooled it, 32 citations in OpenAlex.
- The dark art of light measurement: accurate radiometry for low-level light therapy.Lasers in medical science · 2016Pooled it
- Assessment of the efficiency of new regenerative gel and spray in experimental model systems.BMC pharmacology & toxicology · 2026Article
- Effects of photobiomodulation therapy with red LED on inflammatory cells during the healing of skin burns.Lasers in medical science · 2022Article
- Keratinocyte and Fibroblast Wound Healing In Vitro Is Repressed by Non-Optimal Conditions but the Reparative Potential Can Be Improved by Water-Filtered Infrared A.Biomedicines · 2021Article
- Experimental models and methods for cutaneous wound healing assessment.International journal of experimental pathology · 2020Review
- Efficacy of negative pressure wound therapy using vacuum-assisted closure combined with photon therapy for management of diabetic foot ulcers.Therapeutics and clinical risk management · 2018Article
- Effect of non-coherent infrared light (LED, λ945 ± 20 nm) on bone repair in diabetic rats-morphometric and spectral analyses.Lasers in medical science · 2017Article
- Refining analgesia strategies using lasers.Lab animal · 2015Article
- Phototherapy improves wound healing in rats subjected to high-fat diet.Lasers in medical science · 2015Article
Corrections and comments
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Authors and funding
6 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundVarious studies have shown that phototherapy promotes the healing of cutaneous wounds.
objectiveTo investigate the effect of phototherapy on healing of cutaneous wounds in nourished and undernourished rats.
methodsForty rats, 20 nourished plus 20 others rendered marasmus with undernourishment, were assigned to four equal groups: nourished sham, nourished Light Emitting Diode treated, undernourished sham and undernourished Light Emitting Diode treated. In the two treated groups, two 8-mm punch wounds made on the dorsum of each rat were irradiated three times per week with 3 J/cm2 sq cm of combined 660 and 890 nm light; wounds in the other groups were not irradiated. Wounds were evaluated with digital photography and image analysis, either on day 7 or day 14, with biopsies obtained on day 14 for histological studies.
resultsUndernourishment retarded the mean healing rate of the undernourished sham wounds (p < 0.01), but not the undernourished Light emission diode treated wounds, which healed significantly faster (p < 0.001) and as fast as the two nourished groups. Histological analysis showed a smaller percentage of collagen in the undernourished sham group compared with the three other groups, thus confirming our photographic image analysis data.
conclusionPhototherapy reverses the adverse healing effects of undernourishment. Similar beneficial effects may be achieved in patients with poor nutritional status.
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