Evidence map›Paper›PMID 25387490›Full record

ArticleAnais brasileiros de dermatologia

Dermatitis herpetiformis: pathophysiology, clinical presentation, diagnosis and treatment.

Marcos Vinícius Clarindo, Adriana Tomazzoni Possebon, Emylle Marlene Soligo, Hirofumi Uyeda, Roseli Terezinha Ruaro, Julio Cesar Empinotti

Open access · goldAbstract read
In one paragraph

Article in Anais brasileiros de dermatologia. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
2.9field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 71 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Etiopathogenesis of dermatitis herpetiformis.Postepy dermatologii i alergologii · 2022
    Review
  6. Review
  7. Review
  8. Article
  9. Review
  10. Review
  11. Review
  12. Article
  13. Article
  14. Review
  15. Dermatitis Herpetiformis: Novel Perspectives.Frontiers in immunology · 2019
    Review
  16. Dermatitis herpetiformis in an African woman.The Pan African medical journal · 2018
    Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Marcos Vinícius ClarindoWest Paraná State University, Cascavel, PR, Brazil.
Adriana Tomazzoni PossebonWest Paraná State University, Cascavel, PR, Brazil.
Emylle Marlene SoligoWest Paraná State University, Cascavel, PR, Brazil.
Hirofumi UyedaWest Paraná State University, Cascavel, PR, Brazil.
Roseli Terezinha RuaroWest Paraná State University, Cascavel, PR, Brazil.
Julio Cesar EmpinottiWest Paraná State University, Cascavel, PR, Brazil.
Universidade Estadual do Paraná · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Researches on DH have shown that it is not just a bullous skin disease, but a cutaneous-intestinal disorder caused by hypersensitivity to gluten. Exposure to gluten is the starting point of an inflammatory cascade capable of forming autoantibodies that are brought to the skin, where they are deposited, culminating in the formation of skin lesions. These lesions are vesico-bullous, pruritic, and localized especially on elbows, knees and buttocks, although atypical presentations can occur. Immunofluorescence of perilesional area is considered the gold standard for diagnosis, but serological tests help in cases where it is negative. Patients who follow gluten-free diets have better control of symptoms on the skin and intestine, as well as lower risks of progression to lymphoma. Dapsone remains the main drug for treatment, but it requires monitoring of possible side effects, some potentially lethal.

Indexed as

Celiac DiseaseDapsoneDermatitis HerpetiformisDiet, Gluten-FreeFemaleFluorescent Antibody Technique, DirectFolic Acid AntagonistsHumansMaleSkinDapsoneFolic Acid Antagonists

Identifiers

PMID25387490
PMCPMC4230654
OpenAlexW2096443782

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.