ArticleJournal of neurotrauma2015
Functional near-infrared spectroscopy reveals reduced interhemispheric cortical communication after pediatric concussion.
Article in Journal of neurotrauma, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 1 of them a synthesis that pooled it.
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Who cites it
21 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Traumatic brain injury biomarkers in pediatric patients: a systematic review.Neurosurgical review · 2022Pooled it
- Direct Evidence for the Feedforward Neurovascular Coupling Mechanism in Humans During Task Onset: An EEG-fNIRS-TCD Multimodal Imaging Study.Sensors (Basel, Switzerland) · 2026Article
- Prefrontal Cortex Activity During Gait in People With Persistent Symptoms After Concussion.Neurorehabilitation and neural repair · 2024Article
- Article
- Detection of low-frequency oscillations in neonatal piglets with speckle contrast diffuse correlation tomography.Journal of biomedical optics · 2023Article
- Impact of averaging fNIRS regional coherence data when monitoring people with long term post-concussion symptoms.Neurophotonics · 2023Article
- Cerebral Hemodynamics and Microvasculature Changes in Relation to White Matter Microstructure After Pediatric Mild Traumatic Brain Injury: An A-CAP Pilot Study.Neurotrauma reports · 2023Article
- Treatment of Persistent Postconcussion Syndrome With Repetitive Transcranial Magnetic Stimulation Using Functional Near-Infrared Spectroscopy as a Biomarker of Response: Protocol for a Randomized Controlled Clinical Trial.JMIR research protocols · 2022Article
- Flexibility ofFrontiers in cellular neuroscience · 2022Article
- Loss of Motor Stability After Sports-Related Concussion: Opportunities for Motor Learning Strategies to Reduce Musculoskeletal Injury Risk.Sports medicine (Auckland, N.Z.) · 2021Review
- Tomographic Task-Related Functional Near-Infrared Spectroscopy in Acute Sport-Related Concussion: An Observational Case Study.International journal of molecular sciences · 2020Observational
- Pre-frontal Cortex Oxygenation Changes During Aerobic Exercise in Elite Athletes Experiencing Sport-Related Concussion.Frontiers in human neuroscience · 2020Article
- Physiological Vibration Acceleration (Phybrata) Sensor Assessment of Multi-System Physiological Impairments and Sensory Reweighting Following Concussion.Medical devices (Auckland, N.Z.) · 2020Article
- Evaluating Motor Control Improves Discrimination of Adolescents with and without Sports Related Concussion.Journal of motor behavior · 2020Article
- Using Functional Near-Infrared Spectroscopy to Study the Effect of Repetitive Transcranial Magnetic Stimulation in Concussion: A Two-Patient Case Study.Frontiers in neurology · 2019Article
- Microstructural neuroimaging of white matter tracts in persistent post-concussion syndrome: A prospective controlled cohort study.NeuroImage. Clinical · 2019Article
- Reduced Functional Connectivity in Adults with Persistent Post-Concussion Symptoms: A Functional Near-Infrared Spectroscopy Study.Journal of neurotrauma · 2018Article
- Cerebral Perfusion Changes in Post-Concussion Syndrome: A Prospective Controlled Cohort Study.Journal of neurotrauma · 2017Article
- Application of optical methods in the monitoring of traumatic brain injury: A review.Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism · 2016Review
- Article
Corrections and comments
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Concussion, or mild traumatic brain injury (mTBI), is a growing concern, especially among the pediatric population. By age 25, as many as 30% of the population are likely to have had a concussion. Many result in long-term disability, with some evolving to postconcussion syndrome. Treatments are being developed, but are difficult to assess given the lack of measures to quantitatively monitor concussion. There is no accepted quantitative imaging metric for monitoring concussion. We hypothesized that because cognitive function and fiber tracks are often impacted in concussion, interhemispheric brain communication may be impaired. We used functional near-infrared spectroscopy (fNIRS) to quantify functional coherence between the left and right motor cortex as a marker of interhemispheric communication. Studies were undertaken during the resting state and with a finger-tapping task to activate the motor cortex. Pediatric patients (ages 12-18) had symptoms for 31-473 days, compared to controls, who have not had reported a previous concussion. We detected differences between patients and controls in coherence between the contralateral motor cortices using measurements of total hemoglobin and oxy-hemoglobin with a p<0.01 (n=8, control; n=12 mTBI). Given the critical need for a quantitative biomarker for recovery after a concussion, we present these data to highlight the potential of fNIRS coupled with interhemispheric coherence analysis as a biomarker of concussion injury.
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