ReviewAnnual review of animal biosciences2013
The equine endometrial cup reaction: a fetomaternal signal of significance.
Review in Annual review of animal biosciences, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
15 citing papers in PubMed, 52 citations in OpenAlex.
- Comparative analysis of the transcriptome and methylome in distinct trophoblast populations at the time of embryo implantation in mares.BMC genomics · 2026Article
- Stromal resistance to placental invasion is a derived trait in ruminants.The Journal of reproduction and development · 2026Review
- Shifts between pro-inflammatory and anti-inflammatory profiles in pregnant mares: a review of physiological functions.Frontiers in veterinary science · 2025Review
- Decidual cells and decidualization in the carnivoran endotheliochorial placenta.Frontiers in cell and developmental biology · 2023Review
- Evolution of Placental Hormones: Implications for Animal Models.Frontiers in endocrinology · 2022Review
- The transcriptome landscapes of allantochorion and vitelline-chorion in equine day 30 conceptus.Frontiers in cell and developmental biology · 2022Article
- Equine pregnancy-specific glycoprotein CEACAM49 secreted by endometrial cup cells activates TGFB.Reproduction (Cambridge, England) · 2020Article
- Label-Free Mass Spectrometry-Based Quantitative Proteomics Analysis of Serum Proteins During Early Pregnancy in Jennies (Frontiers in veterinary science · 2020Article
- Effects of dietary L-arginine supplementation to early pregnant mares on conceptus diameter-Preliminary findings.Reproduction in domestic animals = Zuchthygiene · 2019Article
- Characterization of the placental transcriptome through mid to late gestation in the mare.PloS one · 2019Article
- Dynamic changes in gene expression and signalling during trophoblast development in the horseReproduction (Cambridge, England) · 2018Article
- Glial Cells Missing 1 Regulates Equine Chorionic Gonadotrophin Beta SubunitFrontiers in endocrinology · 2018Article
- SMAD1/5 signaling in the early equine placenta regulates trophoblast differentiation and chorionic gonadotropin secretion.Endocrinology · 2014Article
- Paternally expressed genes predominate in the placenta.Proceedings of the National Academy of Sciences of the United States of America · 2013Article
- Placental contribution to the endocrinology of gestation and parturition.Animal reproductionArticle
Corrections and comments
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Authors and funding
4 authors at 2 institutions in 2 countries.
Funding
Abstract
A remarkable feature of equine pregnancy is the development of the invasive trophoblast of the chorionic girdle and its formation of the gonadotrophin-secreting endometrial cup cells in early gestation. The details of this process have been revealed only slowly over the past century, since the first description of the endometrial cups in 1912. This centennial presents an opportunity to review the characteristics of the cells and molecules involved in this early, critical phase of placentation in the mare. The invasiveness of the chorionic girdle trophoblast appears to represent an atavistic attribute more commonly associated with the hemochorial placentae of primates and rodents but not with the more recently derived epitheliochorial placentae of the odd-toed ungulates. The nature of and raison d'être for the strong fetal signals transmitted to the mare by the endometrial cup reaction, and her responses to these messages, are the subject of the present review.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.