Evidence map›Paper›PMID 25386720›Full record

ArticleJournal of neurotrauma2021

Inhibition of Cytosolic Phospholipase A

Nai-Kui Liu, James S Byers, Tom Lam, Qing-Bo Lu, Dale R Sengelaub, Xiao-Ming Xu

Open access · greenAbstract read
In one paragraph

Article in Journal of neurotrauma, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
1.5field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 32 citations in OpenAlex.

  1. Arachidonic acid metabolism in spinal cord injury.Journal of advanced research · 2026
    Review
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  9. Regulation of skeletal myogenesis in C2C12 cells through modulation of Pax7, MyoD, and myogenin via different low-frequency electromagnetic field energies.Technology and health care : official journal of the European Society for Engineering and Medicine · 2022
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Nai-Kui LiuSpinal Cord and Brain Injury Research Group, Stark Neurosciences Research Institute, Department of Neurological Surgery and Goodman Campbell Brain and Spine, Indiana University School of Medicine, Indianapolis, Indiana, USA.
James S ByersProgram in Neuroscience and Department of Psychological and Brain Sciences, Indiana University, Bloomington, Indiana, USA.
Tom LamIndiana University School of Medicine, Bloomington, Indiana, USA.
Qing-Bo LuSpinal Cord and Brain Injury Research Group, Stark Neurosciences Research Institute, Department of Neurological Surgery and Goodman Campbell Brain and Spine, Indiana University School of Medicine, Indianapolis, Indiana, USA.
Dale R SengelaubProgram in Neuroscience and Department of Psychological and Brain Sciences, Indiana University, Bloomington, Indiana, USA.
Xiao-Ming XuSpinal Cord and Brain Injury Research Group, Stark Neurosciences Research Institute, Department of Neurological Surgery and Goodman Campbell Brain and Spine, Indiana University School of Medicine, Indianapolis, Indiana, USA.
Indiana University Bloomington · USIndiana University – Purdue University Indianapolis · US

Funding

INDIANA CLINICAL AND TRANSLATIONAL SCIENCE INSTITUTE (UL1): BPCAUL1RR025761 · NCRR · INDIANA UNIVERSITY INDIANAPOLIS · PI SHEKHAR, ANANTHA · 2008 to 2011
$21.0M
PKC inhibition-mediated spinal cord regenerationR01NS052290 · NINDS · UNIVERSITY OF LOUISVILLE · PI XU, XIAO-MING · 2005 to 2009
$1.8M
Tissue engineering in spinal cord regenerationR01NS050243 · NINDS · VIRGINIA COMMONWEALTH UNIVERSITY · PI WEN, XUEJUN · 2007 to 2011
$1.7M
Role of phospholipase A2 in spinal cord secondary injuryR01NS059622 · NINDS · INDIANA UNIVERSITY INDIANAPOLIS · PI XU, XIAO-MING · 2009 to 2013
$1.6M
NCRR NIH HHS UL1 RR025761NINDS NIH HHS R01 NS050243NINDS NIH HHS R01 NS052290NINDS NIH HHS R01 NS059622
6 · The paper itself

Abstract

Surviving motoneurons undergo dendritic atrophy after spinal cord injury (SCI), suggesting an important therapeutic target for neuroprotective strategies to improve recovery of function after SCI. Our previous studies showed that cytosolic phospholipase A

Indexed as

AnimalsArachidonic AcidsEnzyme InhibitorsFemaleMiceMice, Inbred C57BLMice, KnockoutMotor NeuronsMuscular AtrophyNeuroprotective AgentsPhospholipase A2 InhibitorsPhospholipases A2, CytosolicSpinal Cord InjuriesArachidonic AcidsarachidonyltrifluoromethaneEnzyme InhibitorsNeuroprotective AgentsPhospholipase A2 InhibitorsPhospholipases A2, CytosolicatrophycPLA2dendritesmorphologyneuroprotection

Identifiers

PMID25386720
PMCPMC9208724
OpenAlexW2075246910

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.