Evidence map›Paper›PMID 25386693›Full record

ArticleNutrients2014

Polyunsaturated fatty acid composition of maternal diet and erythrocyte phospholipid status in Chilean pregnant women.

Karla A Bascuñán, Rodrigo Valenzuela, Rodrigo Chamorro, Alejandra Valencia, Cynthia Barrera, Claudia Puigrredon, Jorge Sandoval, Alfonso Valenzuela

Open access · goldAbstract read
In one paragraph

Article in Nutrients, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
2.1field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 33 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Karla A BascuñánDepartment of Nutrition, Faculty of Medicine, University of Chile, Av. Independencia 1027, Independencia, Santiago 8380453, Chile. kbascunan@med.uchile.cl.
Rodrigo ValenzuelaDepartment of Nutrition, Faculty of Medicine, University of Chile, Av. Independencia 1027, Independencia, Santiago 8380453, Chile. rvalenzuelab@med.uchile.cl.
Rodrigo ChamorroDepartment of Nutrition, Faculty of Medicine, University of Chile, Av. Independencia 1027, Independencia, Santiago 8380453, Chile. rodrigochamorro@med.uchile.cl.
Alejandra ValenciaDepartment of Nutrition, Faculty of Medicine, University of Chile, Av. Independencia 1027, Independencia, Santiago 8380453, Chile. avalencia2@gmail.com.
Cynthia BarreraDepartment of Nutrition, Faculty of Medicine, University of Chile, Av. Independencia 1027, Independencia, Santiago 8380453, Chile. cynthia.barrera@gmail.com.
Claudia PuigrredonObstetrics and Gynecology Department, Clinical Hospital of the University of Chile, Av. Santos Dumont 999, Independencia, Santiago 8380453, Chile. cpuigrredon@hcuch.cl.
Jorge SandovalObstetrics and Gynecology Department, Clinical Hospital of the University of Chile, Av. Santos Dumont 999, Independencia, Santiago 8380453, Chile. jsandoval@hcuch.cl.
Alfonso ValenzuelaLipid Center, Institute of Nutrition and Food Technology (INTA), University of Chile, Av. El Líbano 5524, Macul, Santiago 8380453, Chile. avalenzu@inta.uchile.cl.
University of Chile · CLUniversidad de Santiago de Chile · CLHospital del Salvador · CL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Chilean diets are characterized by a low supply of n-3 polyunsaturated fatty acids (n-3 PUFA), which are critical nutrients during pregnancy and lactation, because of their role in brain and visual development. DHA is the most relevant n-3 PUFA in this period. We evaluated the dietary n-3 PUFA intake and erythrocyte phospholipids n-3 PUFA in Chilean pregnant women. Eighty healthy pregnant women (20-36 years old) in the 3rd-6th month of pregnancy were included in the study. Dietary assessment was done applying a food frequency questionnaire, and data were analyzed through the Food Processor SQL® software. Fatty acids of erythrocyte phospholipids were assessed by gas-liquid chromatography. Diet composition was high in saturated fat, low in mono- and PUFA, high in n-6 PUFA (linoleic acid) and low in n-3 PUFA (alpha-linolenic acid and DHA), with imbalance in the n-6/n-3 PUFA ratio. Similar results were observed for fatty acids from erythrocyte phospholipids. The sample of Chilean pregnant women showed high consumption of saturated fat and low consumption of n-3 PUFA, which is reflected in the low DHA content of erythrocyte phospholipids. Imbalance between n-6/n-3 PUFA could negatively affect fetal development. New strategies are necessary to improve n-3 PUFA intake throughout pregnancy and breast feeding periods. Furthermore, it is necessary to develop dietary interventions to improve the quality of consumed foods with particular emphasis on n-3 PUFA.

Indexed as

DietMaternal Nutritional Physiological PhenomenaAdultBreast FeedingChileChromatography, GasDietary FatsErythrocytesFatty Acids, Omega-3Fatty Acids, Omega-6FemaleFood AnalysisHumansLactationNutrition AssessmentPhospholipidsDietary FatsFatty Acids, Omega-3Fatty Acids, Omega-6Phospholipids

Identifiers

PMID25386693
PMCPMC4245572
OpenAlexW2124119387

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.