ArticlePloS one2014
Experimental food restriction reveals individual differences in corticosterone reaction norms with no oxidative costs.
Article in PloS one, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
26 citing papers in PubMed, 74 citations in OpenAlex.
- Physiological Responses Vary with Molecular Damage Outcomes after Recovery from Constant Light.Integrative and comparative biology · 2025Article
- Baseline glucocorticoids alone do not predict reproductive success across years, but in interaction with enzymatic antioxidants.Ecology and evolution · 2024Article
- HPA flexibility andPhilosophical transactions of the Royal Society of London. Series B, Biological sciences · 2024Review
- Endocrine flexibility can facilitate or constrain the ability to cope with global change.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2024Review
- Great tits differ in glucocorticoid plasticity in response to spring temperature.Proceedings. Biological sciences · 2022Article
- Quantifying Glucocorticoid Plasticity Using Reaction Norm Approaches: There Still is So Much to Discover!Integrative and comparative biology · 2022Review
- Integrating theoretical and empirical approaches for a robust understanding of endocrine flexibility.The Journal of experimental biology · 2022Article
- Salivary Cortisol Reaction Norms in Zoo-Housed Great Apes: Diurnal Slopes and Intercepts as Indicators of Stress Response Quality.Animals : an open access journal from MDPI · 2022Article
- Article
- Are individuals consistent? Endocrine reaction norms under different ecological challenges.The Journal of experimental biology · 2021Article
- Reactive scope model and emergency life history stage provide useful tools for evaluating the stress responses of native Australian lizards living in disturbed landscapes.Conservation physiology · 2021Article
- Metabolic Rates Predict Baseline Corticosterone and Reproductive Output in a Free-Living Passerine.Integrative organismal biology (Oxford, England) · 2020Article
- Individual variation in phenotypic plasticity of the stress axis.Biology letters · 2019Article
- Antioxidant capacity is repeatable across years but does not consistently correlate with a marker of peroxidation in a free-living passerine bird.Journal of comparative physiology. B, Biochemical, systemic, and environmental physiology · 2019Article
- Telomere attrition: metabolic regulation and signalling function?Biology letters · 2019Article
- Glucocorticoids and "Stress" Are Not Synonymous.Integrative organismal biology (Oxford, England) · 2019Article
- Stress in captive Blue-fronted parrots (Conservation physiology · 2019Article
- Weathering the storm: Do arctic blizzards cause repeatable changes in stress physiology and body condition in breeding songbirds?General and comparative endocrinology · 2018Article
- Effects of Management Related Practices on Turkey Hen Performance Supplemented With Either Original XPC™ or AviCare™.Frontiers in veterinary science · 2018Article
- Dynamic modulation of sociality and aggression: an examination of plasticity within endocrine and neuroendocrine systems.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2017Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 4 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Highly plastic endocrine traits are thought to play a central role in allowing organisms to respond rapidly to environmental change. Yet, not all individuals display the same degree of plasticity in these traits, and the costs of this individual variation in plasticity are unknown. We studied individual differences in corticosterone levels under varying conditions to test whether there are consistent individual differences in (1) baseline corticosterone levels; (2) plasticity in the hormonal response to an ecologically relevant stressor (food restriction); and (3) whether individual differences in plasticity are related to fitness costs, as estimated by oxidative stress levels. We took 25 wild-caught house sparrows into captivity and assigned them to repeated food restricted and control treatments (60% and 110% of their daily food intake), such that each individual experienced both food restricted and control diets twice. We found significant individual variation in baseline corticosterone levels and stress responsiveness, even after controlling for changes in body mass. However, these individual differences in hormonal responsiveness were not related to measures of oxidative stress. These results have implications for how corticosterone levels may evolve in natural populations and raise questions about what we can conclude from phenotypic correlations between hormone levels and fitness measures.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.