ArticlePloS one2014
Mean platelet volume (MPV) predicts middle distance running performance.
Article in PloS one, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 2 of them syntheses that pooled it.
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Who cites it
24 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Effect of Acute and Chronic Aerobic Exercise on Immunological Markers: A Systematic Review.Frontiers in physiology · 2019Pooled it
- The use of platelet indices, plateletcrit, mean platelet volume and platelet distribution width in emergency non-traumatic abdominal surgery: a systematic review.Biochemia medica · 2016Pooled it
- The effect of aerobic exercise on immune biomarkers and symptoms severity and progression in patients with COVID-19: A randomized control trial.Journal of bodywork and movement therapies · 2021Trial
- The Effects of Acute Low-Volume HIIT and Aerobic Exercise on Leukocyte Count and Redox Status.Journal of sports science & medicine · 2018Trial
- Relationships Between Hematological Variables and Bone Metabolism in Elite Female Trail Runners.Healthcare (Basel, Switzerland) · 2026Article
- The Effect of Four-Month Training on Biochemical Variables in Amateur Cross-Country Skiers.Journal of clinical medicine · 2024Article
- Response of Circulating Free Cellular DNA to Repeated Exercise in Men with Type 1 Diabetes Mellitus.Journal of clinical medicine · 2024Article
- Effects of High-Intensity Training on Complete Blood Count, Iron Metabolism, Lipid Profile, Liver, and Kidney Function Tests of Professional Water Polo Players.Diagnostics (Basel, Switzerland) · 2024Article
- Causal relationship between physical activity and platelet traits: a Mendelian randomization study.Frontiers in physiology · 2024Article
- Role of Enhancing Aerobic Capacity in Countering COVID-19-induced Liver Injury in Elderlies.Endocrine, metabolic & immune disorders drug targets · 2024Review
- Improvement of Blood Parameters of Male Rats Exposed to Different Injection Doses of Liquid Chlorophyll.Cureus · 2023Article
- Capillary Blood Recovery Variables in Young Swimmers: An Observational Case Study.International journal of environmental research and public health · 2022Observational
- Review on the Effect of Exercise Training on Immune Function.BioMed research international · 2022Review
- Relationships between Fitness Status and Blood Biomarkers in Professional Soccer Players.Journal of healthcare engineering · 2022Article
- Blood Biomarkers Variations across the Pre-Season and Interactions with Training Load: A Study in Professional Soccer Players.Journal of clinical medicine · 2021Article
- Enhancing oxygenation of patients with coronavirus disease 2019: Effects on immunity and other health-related conditions.World journal of clinical cases · 2021Review
- Article
- Effect of Simulated Matches on Post-Exercise Biochemical Parameters in Women's Indoor and Beach Handball.International journal of environmental research and public health · 2020Article
- The Influence of a Health-Related Fitness Training Program on Motor Performance as Well as Hematological and Biochemical Parameters.International journal of environmental research and public health · 2020Article
- Frequent plateletpheresis donations & its effect on haematological parameters: An observational study.The Indian journal of medical research · 2019Observational
Corrections and comments
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundRunning economy and performance in middle distance running depend on several physiological factors, which include anthropometric variables, functional characteristics, training volume and intensity. Since little information is available about hematological predictors of middle distance running time, we investigated whether some hematological parameters may be associated with middle distance running performance in a large sample of recreational runners.
methodsThe study population consisted in 43 amateur runners (15 females, 28 males; median age 47 years), who successfully concluded a 21.1 km half-marathon at 75-85% of their maximal aerobic power (VO2max). Whole blood was collected 10 min before the run started and immediately thereafter, and hematological testing was completed within 2 hours after sample collection.
resultsThe values of lymphocytes and eosinophils exhibited a significant decrease compared to pre-run values, whereas those of mean corpuscular volume (MCV), platelets, mean platelet volume (MPV), white blood cells (WBCs), neutrophils and monocytes were significantly increased after the run. In univariate analysis, significant associations with running time were found for pre-run values of hematocrit, hemoglobin, mean corpuscular hemoglobin (MCH), red blood cell distribution width (RDW), MPV, reticulocyte hemoglobin concentration (RetCHR), and post-run values of MCH, RDW, MPV, monocytes and RetCHR. In multivariate analysis, in which running time was entered as dependent variable whereas age, sex, blood lactate, body mass index, VO2max, mean training regimen and the hematological parameters significantly associated with running performance in univariate analysis were entered as independent variables, only MPV values before and after the trial remained significantly associated with running time. After adjustment for platelet count, the MPV value before the run (p = 0.042), but not thereafter (p = 0.247), remained significantly associated with running performance.
conclusionThe significant association between baseline MPV and running time suggest that hyperactive platelets may exert some pleiotropic effects on endurance performance.
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