Evidence map›Paper›PMID 25386609›Full record

Trial reportTheScientificWorldJournal2014

A clinical trial to investigate the effect of Cynatine HNS on hair and nail parameters.

Christina Beer, Simon Wood, Robert H Veghte

Open access · goldAbstract readRandomized Controlled Trial
In one paragraph

Trial report in TheScientificWorldJournal, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.3field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 21 citations in OpenAlex.

  1. Nail Supplements: When, How, and Why?Skin appendage disorders · 2025
    Review
  2. Overview and Algorithmic Approach to Management of Male and Female Pattern Hair Loss.Indian journal of plastic surgery : official publication of the Association of Plastic Surgeons of India · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 3 countries.

Christina BeerCB Food Consulting LLC, 320 Sherman Avenue, Salt Lake City, UT 84115, USA.ORCID 0000-0003-4832-9270
Simon WoodFood, Nutrition and Health Program, Faculty of Land and Food Systems, University of British Columbia, 2357 Main Mall, Vancouver, BC, Canada V6T 1Z4 ; School of Public Health, Faculty of Health Sciences, Curtin University, Kent Street, Bentley, WA 6102, Australia.ORCID 0000-0002-3102-1061
Robert H VeghteRoxlor Global LLC, 1013 Centre Road, Suite 106, Wilmington, DE 19805, USA.
University of British Columbia · CAWilmington University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveA new, novel product, Cynatine HNS, was evaluated for its effects as a supplement for improving various aspects of hair and nails in a randomized, double-blind, placebo-controlled clinical trial.

methodsA total of 50 females were included and randomized into two groups. The active group (n = 25) received 2 capsules containing Cynatine HNS, comprised of Cynatine brand keratin (500 mg) plus vitamins and minerals, per day, and the placebo group (n = 25) received 2 identical capsules of maltodextrin per day for 90 days. End points for hair loss, hair growth, hair strength, amino acid composition, and hair luster were measured. End points were also measured for nail strength and the appearance of nails.

resultsThe results show that subjects taking Cynatine HNS showed statistically significant improvements in their hair and nails when compared to placebo.

conclusionCynatine HNS is an effective supplement for improving hair and nails in 90 days or less. EudraCT number is 2014-002645-22.

Indexed as

AdultAgedDietary SupplementsDouble-Blind MethodFemaleHairHumansKeratinsMiddle AgedMineralsNailsVitaminsKeratinsMineralsVitamins

Identifiers

PMID25386609
PMCPMC4214097
OpenAlexW2070343471

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.