Evidence map›Paper›PMID 25386430›Full record

ArticleJournal of clinical and diagnostic research : JCDR2014

Antibiotic resistance in uropathogenic e. Coli strains isolated from non-hospitalized patients in pakistan.

Ihsan Ali, Neeraj Kumar, Safia Ahmed, Javid Iqbal Dasti

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Article in Journal of clinical and diagnostic research : JCDR, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 2 of them syntheses that pooled it.

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6citing papers in PubMed, 2 pooled it
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Article
  5. Study of class 1 integrons in multidrug-resistant uropathogenicIranian journal of basic medical sciences · 2018
    Article
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4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Ihsan AliPhD Student, Department of Microbiology, Quaid-i-Azam University , Islamabad .
Neeraj KumarM. Phil Student, Department of Microbiology, Quaid-i-Azam University , Islamabad .
Safia AhmedProfessor, Department of Microbiology, Quaid-i-Azam University , Islamabad .
Javid Iqbal DastiAssistant Professor, Department of Microbiology, Quaid-i-Azam University , Islamabad .

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo study multidrug-resistance in Uropathogenic E. Coli (UPEC) isolated from non-hospitalized patients. MATERIALS AND

methodsAltogether, 250 bacterial samples were collected from non-hospitalized patients. Their identifications were done on basis of Gram-staining, colony morphology, biochemical testing and PCR. Susceptibility testing was performed by using standard protocols which were recommended by CLSI. STATISTICAL ANALYSIS: For comparisons, statistical analysis was performed by using software, Graphpad Prism 5.0

resultsIn total, 32% (n = 80) of the isolates were identified as E. Coli strains and their susceptibility patterns for different antibiotics were determined. The data indicated least resistance against tazocin [(TZP) -1.25%], amikacin [(AK) -1.8%], tigecycline [(TGC)- 2.5%] and nitrofurantoin [(F) -3.75%]. For both minocycline (MH) and sulzone (SUL), resistance rate was 5%, for gentamicin (CN), it was 16.25%, while higher resistances were observed against cephalothine [(KF)- 70%], cefotaxime [(CTX) -58.5%], ceftazidime [(CAZ)- 57.5%], cefepime [(FEP) -55%], cefuroxime and cefixime [(CXM) (CFM)- 53.75 %]. Resistance against ciprofloxacin (CIP) was 57.5%, for norfloxacine (NOR), it was 52.5% and incase of sparfloxacin (SPX), it remained 55%. High percentage of the isolates were resistant to cotrimoxazole [(SXT) -86%] and Amoxicillin [AMX-CLA (AMC)- 76%]. No resistance against meropenem (MEM) was observed.

conclusionHighest level of drug-resistance was observed against trimethoprim-sulfamethoxazole (TMP-SMZ) among clinical isolates of uropathogenic E. Coli collected from non-hospitalized patients.

Indexed as

Antibiotic susceptibilityBeta-lactamaseCotrimoxazoleE. ColiPlasmidsUPEC

Identifiers

PMID25386430
PMCPMC4225882

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.