Evidence map›Paper›PMID 25386411›Full record

ReviewFrontiers in cellular and infection microbiology2014

Interrelationship between type three secretion system and metabolism in pathogenic bacteria.

Gottfried Wilharm, Christine Heider

Abstract readReview
In one paragraph

Review in Frontiers in cellular and infection microbiology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Article
  2. Animals : an open access journal from MDPI · 2024
    Article
  3. Article
  4. Role of Two-Component System Networks in Pseudomonas aeruginosa Pathogenesis.Advances in experimental medicine and biology · 2022
    Article
  5. Article
  6. Article
  7. Life After Secretion-Frontiers in microbiology · 2019
    Article
  8. Article
  9. Article
  10. Article
  11. Environmental Regulation of Yersinia Pathophysiology.Frontiers in cellular and infection microbiology · 2016
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Gottfried WilharmProject Group P2, Robert Koch-Institute Wernigerode, Germany.
Christine HeiderProject Group P2, Robert Koch-Institute Wernigerode, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Before the advent of molecular biology methods, studies of pathogens were dominated by analyses of their metabolism. Development of molecular biology techniques then enabled the identification and functional characterisation of the fascinating toolbox of virulence factors. Increasing, genomic and proteomic approaches form the basis for a more systemic view on pathogens' functions in the context of infection. Re-emerging interest in the metabolism of pathogens and hosts further expands our view of infections. There is increasing evidence that virulence functions and metabolism of pathogens are extremely intertwined. Type three secretion systems (T3SSs) are major virulence determinants of many Gram-negative pathogens and it is the objective of this review to illustrate the intertwined relationship between T3SSs and the metabolism of the pathogens deploying them.

Indexed as

Bacterial Physiological PhenomenaBacterial Secretion SystemsHost-Pathogen InteractionsAspartate Ammonia-LyaseBacteriaBacterial ProteinsCatalysisFatty AcidsPlasmidsVirulenceAspartate Ammonia-LyaseBacterial ProteinsBacterial Secretion SystemsFatty Acidscross-talkmetabolismPseudomonasSalmonellaT3SStype three secretion systemvirulenceYersinia

Identifiers

PMID25386411
PMCPMC4209828

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.