ArticleAdvances in hematology2014
Prevalence and Specificity of RBC Alloantibodies in Indian Patients Attending a Tertiary Care Hospital.
Article in Advances in hematology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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Who cites it
10 citing papers in PubMed, 36 citations in OpenAlex.
- Characterisation, development, and validation of an in-house antibody cell panel: A prospective cross-sectional study from a tertiary care hospital.The Indian journal of medical research · 2026Article
- Optimization of the antibody identification interval in a high-volume transfusion centre.Vox sanguinis · 2026Article
- Article
- Is It Time to Switch from Conventional Coombs Crossmatching to the Type and Screen Protocol?The Malaysian journal of medical sciences : MJMS · 2023Article
- Analysis of red cell alloimmunization in multi transfused patients at a Tertiary care teaching hospital.Journal of family medicine and primary care · 2020Article
- Red blood cell alloimmunization in multi-transfused patients with chronic kidney disease in Port Harcourt, South-South Nigeria.African health sciences · 2018Article
- A preoperative risk score for transfusion in infrarenal endovascular aneurysm repair to avoid type and cross.Journal of vascular surgery · 2018Article
- Erythrocyte Alloimmunization and Autoimmunization among Blood Donors and Recipients visiting a Tertiary Care Hospital.Journal of clinical and diagnostic research : JCDR · 2017Article
- Determination of the Rh/Kell phenotypes in donor as well as patients might be significant to provide phenotype-matched blood to cancer patients: A retrospective analysis from a tertiary care oncology center in North India.Asian journal of transfusion scienceArticle
- Patient blood management in a neurosurgical patient with anti-e antibody.Asian journal of transfusion scienceArticle
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background. Red blood cell (RBC) alloimmunization results from genetic disparity of RBC antigens between donor and recipients. Data about alloimmunization rate in general patient population is scarce especially from resource limited countries. We undertook this study to determine prevalence and specificity of RBC alloantibodies in patients admitted in various clinical specialties at a tertiary care hospital in North India. Methods. Antibody screening was carried out in 11,235 patients on automated QWALYS 3 platform (Diagast, Loos, France). Antibody identification was carried out with an 11-cell identification panel (ID-Diapanel, Diamed GmbH, Switzerland). Results. The overall incidence of RBC alloimmunization in transfused patients was 1.4% (157/11235), with anti-E being the most common specificity (36.3%), followed by anti-D (16%), anti-c (6.4%), anti-c + E (6.4%), anti-C + D (5.1%), and anti-K (4.5%). The highest incidence of alloimmunization was observed in hematology/oncology patients (1.9%), whereas in other specialties the range was 0.7-1%. Conclusion. As alloimmunization complicates the transfusion outcomes, authors recommend pretransfusion antibody screening and issue of Rh and Kell matched blood to patients who warrant high transfusion requirements in future.
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