Evidence map›Paper›PMID 25386187›Full record

ReviewGastroenterology research and practice2014

Epidemiology characteristics of constipation for general population, pediatric population, and elderly population in china.

Huikuan Chu, Likun Zhong, Hai Li, Xiujing Zhang, Jingzhi Zhang, Xiaohua Hou

3 registry-linked trialsOpen access · goldAbstract readReview
In one paragraph

Review in Gastroenterology research and practice, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 3 registered trials, which are not on this map. Cited by 74 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
74citing papers in PubMed, 5 pooled it
5.4field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03100851 phase3completednot on this mapstarted 2015, after this paper: background citation

Effect of Fermented Milk Containing Lactobacillus Casei Strain Shirota on Chinese People With Constipation

TypeinterventionalSponsorChina Agricultural UniversityRan2015 to 2017Enrolled62ConditionsConstipationArmsLactobacillus casei strain Shirota
NCT06832137 phase1 / phase2not yet recruitingnot on this mapstarted 2025, after this paper: background citation

The Efficacy and Safety of CMTS4520 for Chronic Constipation in Adults: A Randomized, Double-Blind, Placebo-Controlled Trial.

TypeinterventionalSponsorThe Second Hospital of Nanjing Medical UniversityRan2025 to 2030Enrolled100ConditionsConstipationArmsCMTS4520 (dietary fiber probiotics), Placebo
NCT06832176 phase1 / phase2not yet recruitingnot on this mapstarted 2025, after this paper: background citation

The Efficacy and Safety of CMTS4520-Assisted Washed Microbiota Transplantation for Chronic Constipation in Adults: a Randomized, Double-Blind, Placebo-Controlled Trial.

TypeinterventionalSponsorThe Second Hospital of Nanjing Medical UniversityRan2025 to 2030Enrolled100ConditionsConstipationArmsCMTS4520 (dietary fiber probiotics), Placebo
3 · Its place in the literature

Who cites it

74 citing papers in PubMed, 5 syntheses or guidelines pooled it, 138 citations in OpenAlex.

  1. Pooled it
  2. Traditional, complementary and alternative medicine in children constipation: a systematic review.Daru : journal of Faculty of Pharmacy, Tehran University of Medical Sciences · 2019
    Pooled it
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  6. Trial
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  14. Factors Associated With the Severity of Chronic Constipation Among Japanese University Students.JGH open : an open access journal of gastroenterology and hepatology · 2025
    Article
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  17. Review
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14 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Huikuan ChuDivision of Gastroenterology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, 1277 Jiefang Road, Wuhan 430022, China.
Likun ZhongDivision of Gastroenterology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, 1277 Jiefang Road, Wuhan 430022, China.
Hai LiDivision of Gastroenterology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, 1277 Jiefang Road, Wuhan 430022, China.
Xiujing ZhangDivision of Gastroenterology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, 1277 Jiefang Road, Wuhan 430022, China.
Jingzhi ZhangDivision of Gastroenterology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, 1277 Jiefang Road, Wuhan 430022, China.
Xiaohua HouDivision of Gastroenterology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, 1277 Jiefang Road, Wuhan 430022, China.
Union Hospital · CNHuazhong University of Science and Technology · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective. To acquire more data about the epidemiologic characteristics of constipation in different kinds of populations in China. Methods. Using "constipation" and "China" as search terms; relevant papers were searched from January 1995 to April 2014. Data on prevalence, gender, diagnostic criteria, geographical area, educational class, age, race, and physician visit results were extracted and analyzed. Results. 36 trials were included. Prevalence rates of constipation in elderly population (18.1%) and pediatric population (18.8%) were significantly higher than that in general population (8.2%). Prevalence of constipation defined by non-Rome criteria was higher than that by Rome criteria in general population. Prevalence rates of constipation were different for different geographical area. People with less education were predisposed to constipation. In pediatric population, prevalence of constipation was the lowest in children aged 2-6 years. Prevalence of constipation in ethnic minorities was higher than that in Han people. People with constipation were predisposed to FD, haemorrhoid, and GERD. Only 22.2% patients seek medical advice in general population. Conclusions. In China, prevalence of constipation was lower compared with most of other countries. The factors including female gender, diagnostic criteria, geographical area, age, educational class, and race seemed to have major effects on prevalence of constipation.

Identifiers

PMID25386187
PMCPMC4216714
OpenAlexW2078847532

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.