ReviewFrontiers in endocrinology2014
Diversity of the RFamide Peptide Family in Mollusks.
Review in Frontiers in endocrinology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers.
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Who cites it
36 citing papers in PubMed, 59 citations in OpenAlex.
- Autocrine feedback maintains homeostatic neuropeptide expression in a peptidergic hub neuron.bioRxiv : the preprint server for biology · 2026Article
- Tissue-Specific Gene Expression of Digestive Tract Glands inAnimals : an open access journal from MDPI · 2025Article
- Decoding Neuropeptide Complexity: Advancing Neurobiological Insights from Invertebrates to Vertebrates through Evolutionary Perspectives.ACS chemical neuroscience · 2025Review
- Transcriptome analysis of East Asian common octopus, Octopus sinensis, paralarvae.Genes & genomics · 2024Article
- Evolutionary conserved peptide and glycoprotein hormone-like neuroendocrine systems in C. elegans.Molecular and cellular endocrinology · 2024Article
- The FMRF-NH2 gated sodium channel of Biomphalaria glabrata: Localization and expression following infection by Schistosoma mansoni.PLoS neglected tropical diseases · 2023Article
- Identification and Characterization ofBiomolecules · 2023Article
- Concomitant downregulation of neuropeptide genes in a marine snail with consecutive sexual maturation after a nuclear disaster in Japan.Frontiers in endocrinology · 2023Article
- Cell types and molecular architecture of the Octopus bimaculoides visual system.Current biology : CB · 2022Article
- Neurogenesis of the scallop Azumapecten farreri: from the first larval sensory neurons to the definitive nervous system of juveniles.Frontiers in zoology · 2022Article
- Analysis of rhodopsin G protein-coupled receptor orthologs reveals semiochemical peptides for parasite (Schistosoma mansoni) and host (Biomphalaria glabrata) interplay.Scientific reports · 2022Article
- Effect of Air Exposure-Induced Hypoxia on Neurotransmitters and Neurotransmission Enzymes in Ganglia of the ScallopInternational journal of molecular sciences · 2022Article
- Methodological considerations in studying digestive system physiology in octopus: limitations, lacunae and lessons learnt.Frontiers in physiology · 2022Review
- Inhibitory Effect of FMRFamide on NO Production During Immune Defense inFrontiers in immunology · 2022Article
- Functional analysis of LFRFamide signaling in Pacific abalone, Haliotis discus hannai.PloS one · 2022Article
- First Immunodetection of Sensory and Nervous Systems of Parasitic Larvae (Glochidia) of Freshwater BivalveFrontiers in physiology · 2022Article
- FMRF-NHThe Journal of comparative neurology · 2021Article
- Transcriptome Profiling of the Pacific OysterMarine drugs · 2021Article
- Article
- Hormone-like conopeptides - new tools for pharmaceutical design.RSC medicinal chemistry · 2020Review
Corrections and comments
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Authors and funding
2 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Since the initial characterization of the cardioexcitatory peptide FMRFamide in the bivalve mollusk Macrocallista nimbosa, a great number of FMRFamide-like peptides (FLPs) have been identified in mollusks. FLPs were initially isolated and molecularly characterized in model mollusks using biochemical methods. The development of recombinant technologies and, more recently, of genomics has boosted knowledge on their diversity in various mollusk classes. Today, mollusk FLPs represent approximately 75 distinct RFamide peptides that appear to result from the expression of only five genes: the FMRFamide-related peptide gene, the LFRFamide gene, the luqin gene, the neuropeptide F gene, and the cholecystokinin/sulfakinin gene. FLPs display a complex spatiotemporal pattern of expression in the central and peripheral nervous system. Working as neurotransmitters, neuromodulators, or neurohormones, FLPs are involved in the control of a great variety of biological and physiological processes including cardiovascular regulation, osmoregulation, reproduction, digestion, and feeding behavior. From an evolutionary viewpoint, the major challenge will then logically concern the elucidation of the FLP repertoire of orphan mollusk classes and the way they are functionally related. In this respect, deciphering FLP signaling pathways by characterizing the specific receptors these peptides bind remains another exciting objective.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.