Evidence map›Paper›PMID 25386058›Full record

ReviewWorld journal of gastroenterology2014

Prevention of esophageal strictures after endoscopic submucosal dissection.

Shinichiro Kobayashi, Nobuo Kanai, Takeshi Ohki, Ryo Takagi, Naoyuki Yamaguchi, Hajime Isomoto, Yoshiyuki Kasai, Takahiro Hosoi, Kazuhiko Nakao, Susumu Eguchi and 3 more

Registry-linked trialOpen access · hybridAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in World journal of gastroenterology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02703376 (Oral Prednisolone in the Treatment of Esophageal Stricture After Esophageal Surgery), which is not on this map. Cited by 24 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed, 1 pooled it
4.4field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02703376 phase1unknown statusnot on this mapstarted 2016, after this paper: background citation

Oral Prednisolone in the Treatment of Esophageal Stricture After Esophageal Surgery

TypeinterventionalSponsorNagasaki UniversityRan2016 to 2019Enrolled8ConditionsEsophageal Anastomotic StrictureArmsOral Prednisone
3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 1 synthesis or guideline pooled it, 51 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Endoscopic submucosal dissection of a tumor in the upper esophageal sphincter and piriform sinus.VideoGIE : an official video journal of the American Society for Gastrointestinal Endoscopy · 2022
    Article
  10. Article
  11. Prevention of Esophageal Stricture After Whole Circumferential Endoscopic Resection: A Review for Endoscopists.The Turkish journal of gastroenterology : the official journal of Turkish Society of Gastroenterology · 2022
    Review
  12. Article
  13. Article
  14. Article
  15. Fabrication of tissue-engineered cell sheets by automated cell culture equipment.Journal of tissue engineering and regenerative medicine · 2019
    Article
  16. Article
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  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 1 institution in 1 country.

Shinichiro KobayashiShinichiro Kobayashi, Nobuo Kanai, Takeshi Ohki, Ryo Takagi, Naoyuki Yamaguchi, Yoshiyuki Kasai, Takahiro Hosoi, Masayuki Yamato, Teruo Okano, Institute of Advanced Biomedical Engineering and Science, Tokyo Women's Medical University, Tokyo 162-8666, Japan.
Nobuo KanaiShinichiro Kobayashi, Nobuo Kanai, Takeshi Ohki, Ryo Takagi, Naoyuki Yamaguchi, Yoshiyuki Kasai, Takahiro Hosoi, Masayuki Yamato, Teruo Okano, Institute of Advanced Biomedical Engineering and Science, Tokyo Women's Medical University, Tokyo 162-8666, Japan.
Takeshi OhkiShinichiro Kobayashi, Nobuo Kanai, Takeshi Ohki, Ryo Takagi, Naoyuki Yamaguchi, Yoshiyuki Kasai, Takahiro Hosoi, Masayuki Yamato, Teruo Okano, Institute of Advanced Biomedical Engineering and Science, Tokyo Women's Medical University, Tokyo 162-8666, Japan.
Ryo TakagiShinichiro Kobayashi, Nobuo Kanai, Takeshi Ohki, Ryo Takagi, Naoyuki Yamaguchi, Yoshiyuki Kasai, Takahiro Hosoi, Masayuki Yamato, Teruo Okano, Institute of Advanced Biomedical Engineering and Science, Tokyo Women's Medical University, Tokyo 162-8666, Japan.
Naoyuki YamaguchiShinichiro Kobayashi, Nobuo Kanai, Takeshi Ohki, Ryo Takagi, Naoyuki Yamaguchi, Yoshiyuki Kasai, Takahiro Hosoi, Masayuki Yamato, Teruo Okano, Institute of Advanced Biomedical Engineering and Science, Tokyo Women's Medical University, Tokyo 162-8666, Japan.
Hajime IsomotoShinichiro Kobayashi, Nobuo Kanai, Takeshi Ohki, Ryo Takagi, Naoyuki Yamaguchi, Yoshiyuki Kasai, Takahiro Hosoi, Masayuki Yamato, Teruo Okano, Institute of Advanced Biomedical Engineering and Science, Tokyo Women's Medical University, Tokyo 162-8666, Japan.
Yoshiyuki KasaiShinichiro Kobayashi, Nobuo Kanai, Takeshi Ohki, Ryo Takagi, Naoyuki Yamaguchi, Yoshiyuki Kasai, Takahiro Hosoi, Masayuki Yamato, Teruo Okano, Institute of Advanced Biomedical Engineering and Science, Tokyo Women's Medical University, Tokyo 162-8666, Japan.
Takahiro HosoiShinichiro Kobayashi, Nobuo Kanai, Takeshi Ohki, Ryo Takagi, Naoyuki Yamaguchi, Yoshiyuki Kasai, Takahiro Hosoi, Masayuki Yamato, Teruo Okano, Institute of Advanced Biomedical Engineering and Science, Tokyo Women's Medical University, Tokyo 162-8666, Japan.
Kazuhiko NakaoShinichiro Kobayashi, Nobuo Kanai, Takeshi Ohki, Ryo Takagi, Naoyuki Yamaguchi, Yoshiyuki Kasai, Takahiro Hosoi, Masayuki Yamato, Teruo Okano, Institute of Advanced Biomedical Engineering and Science, Tokyo Women's Medical University, Tokyo 162-8666, Japan.
Susumu EguchiShinichiro Kobayashi, Nobuo Kanai, Takeshi Ohki, Ryo Takagi, Naoyuki Yamaguchi, Yoshiyuki Kasai, Takahiro Hosoi, Masayuki Yamato, Teruo Okano, Institute of Advanced Biomedical Engineering and Science, Tokyo Women's Medical University, Tokyo 162-8666, Japan.
Masakazu YamamotoShinichiro Kobayashi, Nobuo Kanai, Takeshi Ohki, Ryo Takagi, Naoyuki Yamaguchi, Yoshiyuki Kasai, Takahiro Hosoi, Masayuki Yamato, Teruo Okano, Institute of Advanced Biomedical Engineering and Science, Tokyo Women's Medical University, Tokyo 162-8666, Japan.
Masayuki YamatoShinichiro Kobayashi, Nobuo Kanai, Takeshi Ohki, Ryo Takagi, Naoyuki Yamaguchi, Yoshiyuki Kasai, Takahiro Hosoi, Masayuki Yamato, Teruo Okano, Institute of Advanced Biomedical Engineering and Science, Tokyo Women's Medical University, Tokyo 162-8666, Japan.
Teruo OkanoShinichiro Kobayashi, Nobuo Kanai, Takeshi Ohki, Ryo Takagi, Naoyuki Yamaguchi, Yoshiyuki Kasai, Takahiro Hosoi, Masayuki Yamato, Teruo Okano, Institute of Advanced Biomedical Engineering and Science, Tokyo Women's Medical University, Tokyo 162-8666, Japan.
Waseda University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Endoscopic mucosal resection (EMR) and endoscopic submucosal dissection (ESD) have recently been accepted as less invasive methods for treating patients with early esophageal cancers such as squamous cell carcinoma and dysplasia of Barrett's esophagus. However, the large defects in the esophageal mucosa often cause severe esophageal strictures, which dramatically reduce the patient's quality of life. Although preventive endoscopic balloon dilatation can reduce dysphagia and the frequency of dilatation, other approaches are necessary to prevent esophageal strictures after ESD. This review describes several strategies for preventing esophageal strictures after ESD, with a particular focus on anti-inflammatory and tissue engineering approaches. The local injection of triamcinolone acetonide and other systemic steroid therapies are frequently used to prevent esophageal strictures after ESD. Tissue engineering approaches for preventing esophageal strictures have recently been applied in basic research studies. Scaffolds with temporary stents have been applied in five cases, and this technique has been shown to be safe and is anticipated to prevent esophageal strictures. Fabricated autologous oral mucosal epithelial cell sheets to cover the defective mucosa similarly to how commercially available skin products fabricated from epidermal cells are used for skin defects or in cases of intractable ulcers. Fabricated autologous oral-mucosal-epithelial cell sheets have already been shown to be safe.

Indexed as

Anti-Inflammatory AgentsCell TransplantationDissectionEsophageal NeoplasmsEsophageal StenosisEsophagectomyEsophagoscopyHumansInjectionsStentsSteroidsTissue EngineeringTissue ScaffoldsTreatment OutcomeAnti-Inflammatory AgentsSteroidsAutologous oral mucosal epithelial cell sheetEndoscopic submucosal dissectionEsophageal strictureSystemic steroid therapy

Identifiers

PMID25386058
PMCPMC4223243
OpenAlexW2113317803

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.