Evidence map›Paper›PMID 25386049›Full record

ReviewWorld journal of gastroenterology2014

Current surgical treatment strategies for hepatocellular carcinoma in North America.

Adeel S Khan, Kathryn J Fowler, William C Chapman

Abstract readReview
In one paragraph

Review in World journal of gastroenterology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
  3. Article
  4. Article
  5. Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Adeel S KhanAdeel S Khan, Department of General and Vascular Surgery, Aurora Bay Care Medical Center, Greenbay, WI 54311, United States.
Kathryn J FowlerAdeel S Khan, Department of General and Vascular Surgery, Aurora Bay Care Medical Center, Greenbay, WI 54311, United States.
William C ChapmanAdeel S Khan, Department of General and Vascular Surgery, Aurora Bay Care Medical Center, Greenbay, WI 54311, United States.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hepatocellular carcinoma (HCC) is an aggressive tumor that often occurs in the setting of chronic liver disease. Many patients do not initially manifest any symptoms of HCC and present late when cure with surgical resection or transplantation is no longer possible. For this reason, patients at high risk for developing HCC are subjected to frequent screening processes. The surgical management of HCC is complex and requires an inter-disciplinary approach. Hepatic resection is the treatment of choice for HCC in patients without cirrhosis and is indicated in some patients with early cirrhosis (Child-Pugh A). Liver transplantation has emerged in the past decade as the standard of care for patients with cirrhosis and HCC meeting Milan criteria and in select patients with HCC beyond Milan criteria. Loco-regional therapy with transarterial chemoembolization, transarterial embolization, radiofrequency ablation and other similar local treatments can be used as neo-adjuvant therapy to downstage HCC to within Milan criteria or as a bridge to transplantation in patients on transplant wait list.

Indexed as

HepatectomyLiver TransplantationCarcinoma, HepatocellularCatheter AblationChemoembolization, TherapeuticChemotherapy, AdjuvantHumansLiver NeoplasmsMagnetic Resonance ImagingNeoadjuvant TherapyNeoplasm StagingNorth AmericaRisk FactorsTreatment OutcomeWaiting ListsHepatocellular carcinomaLiver resectionLiver transplantationRadiofrequency ablationTransarterial chemoembolization

Identifiers

PMID25386049
PMCPMC4223234

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.