Evidence map›Paper›PMID 25385945›Full record

ReviewJournal of diabetes science and technology2015

Are you ready for more insulin concentrations?

Alissa R Segal, Nuha El Sayed

Abstract readReview
In one paragraph

Review in Journal of diabetes science and technology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Trial
  2. Review
  3. Article
  4. Article
  5. Review
  6. Challenges With Insulin in the Inpatient Setting.Diabetes spectrum : a publication of the American Diabetes Association · 2016
    Article
  7. Concentrated insulins: the new basal insulins.Therapeutics and clinical risk management · 2016
    Review
  8. Review
  9. Challenges in Delivering Smaller Doses of Insulin.Diabetes technology & therapeutics · 2015
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Alissa R SegalMCPHS University, Boston, MA, USA Joslin Diabetes Center, Boston, MA, USA alissa.segal@mcphs.edu.
Nuha El SayedJoslin Diabetes Center, Boston, MA, USA Harvard Medical School, Boston, MA, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Practitioners need to prepare for a rapid expansion of new concentrated insulins. For many years, the treatment regimens for patients have been limited to 2 concentrations (100 units/mL and 500 units/mL), which pose challenges to both patients and providers. As the new concentrated insulins are at various stages of development, this manuscript reviews the available information on the new concentrated products. This information was obtained from publications, poster presentations, abstracts, and the manufacturers for the products in earlier stages of development. To have a basis for comparison, it is important to understand the activity profile and the challenges with use of the currently available concentrated insulin, regular insulin 500 units/mL (U500R). We also examine how the newer products may assist clinicians and patients with the difficulties faced with the use of U500R.

Indexed as

Diabetes Mellitus, Type 2HumansHypoglycemic AgentsInsulinHypoglycemic AgentsInsulinconcentrated insulin therapysubcutaneous injectionU-200 degludec insulinU-300 glargine insulinU-500 regular insulin

Identifiers

PMID25385945
PMCPMC4604590

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.