Evidence map›Paper›PMID 25385764›Full record

ArticleNeurorehabilitation and neural repair2015

Paretic Propulsion and Trailing Limb Angle Are Key Determinants of Long-Distance Walking Function After Stroke.

Louis N Awad, Stuart A Binder-Macleod, Ryan T Pohlig, Darcy S Reisman

Abstract read
In one paragraph

Article in Neurorehabilitation and neural repair, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 71 papers.

0numbers the graph read from it
0cells of the map it votes in
71citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

71 citing papers in PubMed.

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  8. Effects of unilateral real-time biofeedback on propulsive forces during gait.Journal of neuroengineering and rehabilitation · 2017
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  13. Exoskeletal-Assisted Training in Veterans With Chronic Stroke: A Pilot Study.Archives of rehabilitation research and clinical translation · 2026
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11 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Louis N AwadUniversity of Delaware, Newark, DE, USA.
Stuart A Binder-MacleodUniversity of Delaware, Newark, DE, USA.
Ryan T PohligUniversity of Delaware, Newark, DE, USA.
Darcy S ReismanUniversity of Delaware, Newark, DE, USA dreisman@udel.edu.

Funding

Subproject Title: Clinical Research Education, Mentoring and Career Development CoreU54GM104941 · NIGMS · UNIVERSITY OF DELAWARE · PI Gregory E Hicks · 2013 to 2026
$60.5M
Pilot Project ProgramP30GM103333 · NIGMS · UNIVERSITY OF DELAWARE · PI BUCHANAN, THOMAS S · 2012 to 2016
$5.7M
PT/PHD Predoctoral Training Program Diversity SupplementT32HD007490 · NICHD · UNIVERSITY OF DELAWARE · PI DARCY S. REISMAN · 1996 to 2026
$3.7M
Fast Treadmill Training/Functional Electrical Stimulation to Improve WalkingR01NR010786 · NINR · UNIVERSITY OF DELAWARE · PI BINDER-MACLEOD, STUART A. · 2007 to 2011
$2.8M
Locomotor Adaptations Following StrokeK01HD050582 · NICHD · UNIVERSITY OF DELAWARE · PI REISMAN, DARCY S. · 2006 to 2010
$645k
NICHD NIH HHS K01 HD050582NICHD NIH HHS K01HD050582NICHD NIH HHS T32 HD007490NICHD NIH HHS T32HD007490NIGMS NIH HHS P30 GM103333NIGMS NIH HHS P30GM103333NIGMS NIH HHS U54 GM104941NIGMS NIH HHS U54GM104941NINR NIH HHS R01 NR010786NINR NIH HHS R01NR010786
6 · The paper itself

Abstract

backgroundElucidation of the relative importance of commonly targeted biomechanical variables to poststroke long-distance walking function would facilitate optimal intervention design.

objectivesTo determine the relative contribution of variables from 3 biomechanical constructs to poststroke long-distance walking function and identify the biomechanical changes underlying posttraining improvements in long-distance walking function.

methodsForty-four individuals >6 months after stroke participated in this study. A subset of these subjects (n = 31) underwent 12 weeks of high-intensity locomotor training. Cross-sectional (pretraining) and longitudinal (posttraining change) regression quantified the relationships between poststroke long-distance walking function, as measured via the 6-Minute Walk Test (6MWT), and walking biomechanics. Biomechanical variables were organized into stance phase (paretic propulsion and trailing limb angle), swing phase (paretic ankle dorsiflexion and knee flexion), and symmetry (step length and swing time) constructs.

resultsPretraining, all variables correlated with 6MWT distance (rs = .39 to .75, Ps < .05); however, only propulsion (Prop) and trailing limb angle (TLA) independently predicted 6MWT distance, R(2) = .655, F(6, 36) = 11.38, P < .001. Interestingly, only ΔProp predicted Δ6MWT; however, pretraining Prop, pretraining TLA, and ΔTLA moderated this relationship (moderation model R(2)s = .383, .468, .289, respectively).

conclusionsThe paretic limb's ability to generate propulsion during walking is a critical determinant of long-distance walking function after stroke. This finding supports the development of poststroke interventions that target deficits in propulsion and trailing limb angle.

Indexed as

Stroke RehabilitationBiomechanical PhenomenaCross-Sectional StudiesExercise TestFemaleHumansLegLongitudinal StudiesMaleMiddle AgedParesisRegression AnalysisStrokeTreatment OutcomeWalkingbiomechanicsgaithemiparesisrehabilitationstrokewalking

Identifiers

PMID25385764
PMCPMC4426250

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.