ReviewLab on a chip2015
Interplay of physical mechanisms and biofilm processes: review of microfluidic methods.
Review in Lab on a chip, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 49 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
49 citing papers in PubMed, 176 citations in OpenAlex.
- Physical communication pathways in bacteria: an extra layer to quorum sensing.Biophysical reviews · 2025Review
- Enhancing biofilm disruption and bactericidal efficiency using vancomycin-loaded microbubbles in sonodynamic therapy.JAC-antimicrobial resistance · 2025Article
- CXCL16/CXCR6/TGF-β Feedback Loop Between M-MDSCs and Treg Inhibits Anti-Bacterial Immunity During Biofilm Infection.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025Article
- Unravel the rotational and translational behavior of a single squirmer in flexible polymer solutions at different Reynolds numbers.Communications physics · 2025Article
- Effect of shear rate on earlyBiofilm · 2024Article
- Microfluidic Platform with Precisely Controlled Hydrodynamic Parameters and Integrated Features for Generation of Microvortices to Accurately Form and Monitor Biofilms in Flow.ACS biomaterials science & engineering · 2024Article
- A Metabolomics Approach to Establish the Relationship between the Techno-Functional Properties and Metabolome of Indian Goat Yoghurt.Foods (Basel, Switzerland) · 2024Article
- Impact of carbon sources in airport de-icing compounds on the growth ofFrontiers in microbiology · 2024Article
- Understanding the Influence of Rheology on Biofilm Adhesion and Implication for Food Safety.International journal of food science · 2024Review
- Current examining methods and mathematical models of horizontal transfer of antibiotic resistance genes in the environment.Frontiers in microbiology · 2024Review
- Plants and endophytes interaction: a "secret wedlock" for sustainable biosynthesis of pharmaceutically important secondary metabolites.Microbial cell factories · 2023Review
- Microfluidic techniques for mechanical measurements of biological samples.Biophysics reviews · 2023Review
- Early biofilm and streamer formation is mediated by wall shear stress and surface wettability: A multifactorial microfluidic study.MicrobiologyOpen · 2022Article
- Article
- Engineering aligned human cardiac muscle using developmentally inspired fibronectin micropatterns.Scientific reports · 2021Article
- A Novel Method to Reveal a Ureolytic Biofilm Attachment and In Situ Growth Monitoring by Electrochemical Impedance Spectroscopy.Applied biochemistry and biotechnology · 2021Article
- Home, sweet home: how mucus accommodates our microbiota.The FEBS journal · 2021Review
- A microfluidic platform for in situ investigation of biofilm formation and its treatment under controlled conditions.Journal of nanobiotechnology · 2020Article
- Microfluidics Used as a Tool to Understand and Optimize Membrane Filtration Processes.Membranes · 2020Review
- Beyond Risk: Bacterial Biofilms and Their Regulating Approaches.Frontiers in microbiology · 2020Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 4 institutions in 3 countries.
Funding
Abstract
Bacteria in natural and artificial environments often reside in self-organized, integrated communities known as biofilms. Biofilms are highly structured entities consisting of bacterial cells embedded in a matrix of self-produced extracellular polymeric substances (EPS). The EPS matrix acts like a biological 'glue' enabling microbes to adhere to and colonize a wide range of surfaces. Once integrated into biofilms, bacterial cells can withstand various forms of stress such as antibiotics, hydrodynamic shear and other environmental challenges. Because of this, biofilms of pathogenic bacteria can be a significant health hazard often leading to recurrent infections. Biofilms can also lead to clogging and material degradation; on the other hand they are an integral part of various environmental processes such as carbon sequestration and nitrogen cycles. There are several determinants of biofilm morphology and dynamics, including the genotypic and phenotypic states of constituent cells and various environmental conditions. Here, we present an overview of the role of relevant physical processes in biofilm formation, including propulsion mechanisms, hydrodynamic effects, and transport of quorum sensing signals. We also provide a survey of microfluidic techniques utilized to unravel the associated physical mechanisms. Further, we discuss the future research areas for exploring new ways to extend the scope of the microfluidic approach in biofilm studies.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.