Evidence map›Paper›PMID 25384732›Full record

ArticleAmerican journal of industrial medicine2015

Occupational exposures and longitudinal lung function decline.

Shu-Yi Liao, Xihong Lin, David C Christiani

Open access · bronzeAbstract readComparative Study
In one paragraph

Article in American journal of industrial medicine, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed, 2 pooled it
1.0field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 2 syntheses or guidelines pooled it, 35 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Observational
  5. Article
  6. Review
  7. Risk Factors of FEV₁/FVC Decline in COPD Patients.Journal of Korean medical science · 2025
    Observational
  8. Article
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  15. Rapid FEVJournal of Korean medical science · 2023
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Shu-Yi LiaoHarvard School of Public Health, Boston, Massachusetts.
Xihong Lin
David C Christiani
Harvard University · US

Funding

Translational Research Support CoreP30ES000002 · NIEHS · HARVARD UNIVERSITY (SCH OF PUBLIC HLTH) · PI SUSAN A KORRICK · 1985 to 2026
$44.6M
The Spread of Health Behaviors in the Framingham Heart Study Social NetworkP01AG031093 · NIA · YALE UNIVERSITY · PI MCGUIRE, THOMAS G. · 2008 to 2012
$10.7M
SLEEP AND ENTRAINMENT OF SCN FUNCTIONR01HL064278 · NHLBI · CASE WESTERN RESERVE UNIVERSITY · PI STROHL, KINGMAN PERKINS · 1999 to 2002
$871k
THE FRAMINGHAM HEART STUDY-N01HC25195-268025195-268025195N01HC025195 · HC · TRUSTEES OF BOSTON UNIVERSITY · PI WOLF, PHILIP A · 2002 to 2006
–
NHLBI NIH HHS N01 HC025195NHLBI NIH HHS N01-HC-25195NHLBI NIH HHS N02 HL064278NIA NIH HHS P01 AG 031093NIA NIH HHS P01 AG031093NIEHS NIH HHS ES00002NIEHS NIH HHS P30 ES000002
6 · The paper itself

Abstract

backgroundFew longitudinal studies have been conducted on occupational exposure and lung function. This study investigated occupational dust exposure effects on lung function and whether genetic variants influence such effects.

methodsThe study population (1,332 participants) was from the Framingham Heart Study, in which participant lung function measures were available from up to five examinations over nearly 17 years. Occupational dust exposures were classified into "more" and "less" likely dust exposure. We used linear mixed effects models for the analysis.

resultsParticipants with more likely dust exposure had a mean 4.5 mL/year excess loss rate of FEV1 over time. However, occupational dust exposures alone or interactions with age or time had no significant effect on FEV1 /FVC. No statistically significant effects of genetic modifications in the different subgroups were identified for FEV1 loss.

conclusionsOccupational dust exposures may accelerate the rate of FEV1 loss but not FEV1 /FVC loss.

Indexed as

DustAdultAgedFemaleForced Expiratory VolumeGenotypeHumansLinear ModelsLongitudinal StudiesLungMaleMassachusettsMiddle AgedOccupational DiseasesOccupational ExposurePolymorphism, GeneticDustchronic obstructive pulmonary diseaseenvironmental healthenvironmental lung diseaseforced expiratory volume in one secondjob exposure matrixoccupational healthoccupational respiratory disease

Identifiers

PMID25384732
PMCPMC4512740
OpenAlexW1531898924

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.