ArticleToxins2014
Molecular and insecticidal characterization of a novel Cry-related protein from Bacillus thuringiensis toxic against Myzus persicae.
Article in Toxins, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
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Who cites it
17 citing papers in PubMed, 49 citations in OpenAlex.
- A Mechanistic Model of Cry2Ab12 Toxicity AgainstToxins · 2026Article
- Identification, expression, and insecticidal activity analysis of a novel cry toxin gene from Bacillus thuringiensis Gxun777-1.World journal of microbiology & biotechnology · 2026Article
- Aphid-killing bacteria: diversity, origin, mechanisms and biocontrol potential.Frontiers in microbiology · 2026Review
- Article
- Entomopathogenic Bacteria Species and Toxins Targeting Aphids (Hemiptera: Aphididae): A Review.Plants (Basel, Switzerland) · 2025Review
- The Prospect of Hydrolytic Enzymes fromInternational journal of molecular sciences · 2023Review
- Identification of novel aphid-killing bacteria to protect plants.Microbial biotechnology · 2022Article
- Dynamics in Pest Status of Phytophagous Stink Bugs in the Neotropics.Neotropical entomology · 2022Review
- Complete genome sequence of Bacillus thuringiensis BR145, a strain with insecticidal activity against Lepidoptera pests.Genetics and molecular biology · 2022Article
- Proteomic and metabolomic approach to rationalize the differential mosquito larvicidal toxicity inAnalytical science advances · 2021Article
- ORFograph: search for novel insecticidal protein genes in genomic and metagenomic assembly graphs.Microbiome · 2021Article
- Characterization of transgenic rice expressing fusion protein Cry1Ab/Vip3A for insect resistance.Scientific reports · 2018Article
- Cry64Ba and Cry64Ca, Two ETX/MTX2-Type Bacillus thuringiensis Insecticidal Proteins Active against Hemipteran Pests.Applied and environmental microbiology · 2018Article
- Aphicidal Activity of Surfactants Produced byFrontiers in microbiology · 2018Article
- Article
- Food safety knowledge on the Bt mutant protein Cry8Ka5 employed in the development of coleopteran-resistant transgenic cotton plants.Bioengineered · 2015Review
- Review
Corrections and comments
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Authors and funding
6 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
This study describes the insecticidal activity of a novel Bacillus thuringiensis Cry-related protein with a deduced 799 amino acid sequence (~89 kDa) and ~19% pairwise identity to the 95-kDa-aphidicidal protein (sequence number 204) from patent US 8318900 and ~40% pairwise identity to the cancer cell killing Cry proteins (parasporins Cry41Ab1 and Cry41Aa1), respectively. This novel Cry-related protein contained the five conserved amino acid blocks and the three conserved domains commonly found in 3-domain Cry proteins. The protein exhibited toxic activity against the green peach aphid, Myzus persicae (Sulzer) (Homoptera: Aphididae) with the lowest mean lethal concentration (LC₅₀ = 32.7 μg/mL) reported to date for a given Cry protein and this insect species, whereas it had no lethal toxicity against the Lepidoptera of the family Noctuidae Helicoverpa armigera (Hübner), Mamestra brassicae (L.), Spodoptera exigua (Hübner), S. frugiperda (J.E. Smith) and S. littoralis (Boisduval), at concentrations as high as ~3.5 μg/cm². This novel Cry-related protein may become a promising environmentally friendly tool for the biological control of M. persicae and possibly also for other sap sucking insect pests.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.