ArticleEnvironmental science & technology2014
Temporal variability of polybrominated diphenyl ether (PBDE) serum concentrations over one year.
Article in Environmental science & technology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
18 citing papers in PubMed, 1 synthesis or guideline pooled it, 35 citations in OpenAlex.
- Developmental PBDE Exposure and IQ/ADHD in Childhood: A Systematic Review and Meta-analysis.Environmental health perspectives · 2017Pooled it
- Flame retardant biomarker changes with furniture replacement after flammability standard update.Environmental pollution (Barking, Essex : 1987) · 2026Article
- Halogenated flame retardant exposure was associated with pediatric gut microbiome profiles in a Canadian cohort.Gut microbes reports · 2026Article
- Associations between gestational polybrominated diphenyl ether (PBDE) serum concentrations and child sleep outcomes from ages 2-8 years.Environmental research · 2025Article
- Decoding the exposome: data science methodologies and implications in exposome-wide association studies (ExWASs).Exposome · 2024Article
- A meta-analysis of randomized controlled studies on the hepatoxicity induced by polybrominated diphenyl ethers (PBDEs) in rats and mice.Current research in toxicology · 2023Article
- Reproductive outcomes associated with flame retardants among couples seeking fertility treatment: A paternal perspective.Environmental research · 2021Article
- Exploring reproductive associations of serum polybrominated diphenyl ether and hydroxylated brominated diphenyl ether concentrations among women undergoing in vitro fertilization.Human reproduction (Oxford, England) · 2020Article
- Evaluating the Use of Silicone Wristbands To Measure Personal Exposure to Brominated Flame Retardants.Environmental science & technology · 2018Article
- Toward Capturing the Exposome: Exposure Biomarker Variability and Coexposure Patterns in the Shared Environment.Environmental science & technology · 2018Article
- Bias Amplification in Epidemiologic Analysis of Exposure to Mixtures.Environmental health perspectives · 2018Article
- Polybrominated diphenyl ethers (PBDEs) and hydroxylated PBDE metabolites (OH-PBDEs): A six-year temporal trend in Northern California pregnant women.Chemosphere · 2018Article
- Prenatal Serum Concentrations of Brominated Flame Retardants and Autism Spectrum Disorder and Intellectual Disability in the Early Markers of Autism Study: A Population-Based Case-Control Study in California.Environmental health perspectives · 2017Article
- A Case-Control Study of Maternal Polybrominated Diphenyl Ether (PBDE) Exposure and Cryptorchidism in Canadian Populations.Environmental health perspectives · 2017Article
- Associations between urinary diphenyl phosphate and thyroid function.Environment international · 2017Article
- Polybrominated diphenyl ether exposure and reproductive hormones in North American men.Reproductive toxicology (Elmsford, N.Y.) · 2016Article
- Contemporary Issues in Exposure Assessment Using Biomonitoring.Current epidemiology reports · 2016Article
- Polybrominated Diphenyl Ether Exposure and Thyroid Function Tests in North American Adults.Environmental health perspectives · 2016Article
Corrections and comments
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Authors and funding
6 authors at 2 institutions in 1 country.
Funding
Abstract
Polybrominated diphenyl ethers (PBDEs) are flame retardant chemicals used in consumer products. They are common contaminants in human serum and associated with adverse health effects. Our objectives were to characterize PBDE serum concentrations in a New England cohort and assess temporal variability of this exposure biomarker over a one-year period. We collected three repeated measurements at six-month intervals from 52 office workers from the greater Boston (MA, United States) area from 2010 to 2011. The intraclass correlation coefficient for BDEs 28, 47, 99, 100, and 153 ranged from 0.87 to 0.99, indicating that a single serum measurement can reliably estimate exposure over a one-year period. This was true for both lipid adjusted and nonlipid adjusted concentrations. The kappa statistics, quantifying the level of agreement of categorical exposure classification, based on medians, tertiles, or quartiles ranged from 0.67 to 0.90. Some congeners showed nonsignificant increases from sampling round 1 (winter) to round 2 (summer) and significant decreases from round 2 to round 3 (winter). This study highlights the high reliability of a single serum PBDE measurement for use in human epidemiologic studies.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.